ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005856
Name cytoskeleton
Type cellular component
No. of Genes in ADHDgene  56
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 56)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FLNC filamin C, gamma 7q32-q35 1(0/0/1) IEA
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 1(1/0/0) ISS[7545544]
DCLK2 doublecortin-like kinase 2 4q31.3 1(0/0/1) IEA

Genes from other sources Help (count: 53)

Approved Symbol Approved Name Source Evidence[PMID]
SPIRE1 spire-type actin nucleation factor 1 Mapped by CNV IEA
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa Mapped by significant region IEA
TWF2 twinfilin actin-binding protein 2 Mapped by LD-proxy IEA
IVNS1ABP influenza virus NS1A binding protein Mapped by significant region; Mapped by PBA pathway IEA
TMSB4Y thymosin beta 4, Y-linked Mapped by PBA pathway IEA
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region NAS[10721722]
RAI14 retinoic acid induced 14 Mapped by significant region IEA
TAOK2 TAO kinase 2 Mapped by CNV IEA
TBCEL tubulin folding cofactor E-like Mapped by significant region IEA
NF2 neurofibromin 2 (merlin) Mapped by PBA pathway TAS[8379998]
STOM stomatin Mapped by significant region IDA[1547348]
KIAA1731 KIAA1731 Mapped by significant region IDA
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated Mapped by significant region IEA
FRMD8 FERM domain containing 8 Mapped by significant region IEA
BICD2 bicaudal D homolog 2 (Drosophila) Mapped by significant region IEA
PTPN3 protein tyrosine phosphatase, non-receptor type 3 Mapped by significant region IEA
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV TAS[19565474]
LMOD2 leiomodin 2 (cardiac) Mapped by CNV IEA
ELMOD1 ELMO/CED-12 domain containing 1 Mapped by significant region IEA
SSH3 slingshot protein phosphatase 3 Mapped by significant region IEA
HSBP1 heat shock factor binding protein 1 Mapped by CNV; Mapped by significant region IEA
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) Mapped by significant region IEA
ACTL7A actin-like 7A Mapped by significant region IEA
SPIRE2 spire-type actin nucleation factor 2 Mapped by significant region IEA
FGD3 FYVE, RhoGEF and PH domain containing 3 Mapped by significant region IEA
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 Mapped by PBA pathway IEA
EPB41L4B erythrocyte membrane protein band 4.1 like 4B Mapped by significant region IEA
MPRIP myosin phosphatase Rho interacting protein Mapped by significant region IEA
COTL1 coactosin-like 1 (Dictyostelium) Mapped by CNV; Mapped by significant region IEA
TNS1 tensin 1 Mapped by significant region IEA
RIN1 Ras and Rab interactor 1 Mapped by significant region IEA
KLHL1 kelch-like family member 1 Mapped by CNV IEA
ARPC5L actin related protein 2/3 complex, subunit 5-like Mapped by significant region IEA
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy TAS[19565474]
MPZL2 myelin protein zero-like 2 Mapped by significant region TAS[9585423]
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) Mapped by CNV IEA
POTEKP POTE ankyrin domain family, member K, pseudogene Mapped by significant region IEA
TGFB1I1 transforming growth factor beta 1 induced transcript 1 Mapped by PBA pathway IEA
SORBS3 sorbin and SH3 domain containing 3 Mapped by PBA pathway IEA
RAPSN receptor-associated protein of the synapse Mapped by LD-proxy IEA
SPEF1 sperm flagellar 1 Mapped by CNV IEA
CTTN cortactin Mapped by significant region IEA
PPL periplakin Mapped by significant region IEA
LLGL1 lethal giant larvae homolog 1 (Drosophila) Mapped by significant region TAS[7542763]
PTPN14 protein tyrosine phosphatase, non-receptor type 14 Mapped by Literature SNP IEA
FHOD3 formin homology 2 domain containing 3 Mapped by significant region IEA
BASP1 brain abundant, membrane attached signal protein 1 Mapped by significant region TAS[9749536]
RDX radixin Mapped by significant region IEA
TPM3P4 tropomyosin 3 pseudogene 4 Mapped by significant region IEA
SNTG2 syntrophin, gamma 2 Mapped by CNV IEA
NEXN nexilin (F actin binding protein) Mapped by PBA pathway IEA
UXT ubiquitously-expressed, prefoldin-like chaperone Mapped by PBA pathway IDA[12762840]
CLNS1A chloride channel, nucleotide-sensitive, 1A Mapped by significant region IEA