ADHDgene Database

Gene Report

Basic Info

Approved Symbol	DCLK2
Previous Symbol	DCAMKL2
Symbol Alias	MGC45428, DCDC3, DCDC3B, DCK2
Approved Name	doublecortin-like kinase 2
Previous Name	doublecortin and CaM kinase-like 2
Location	4q31.3
Position	chr4:150999426-151178609, +
External Links	HGNC: 19002 Entrez Gene: 166614 Ensembl: ENSG00000170390 UCSC: uc003ilm.3
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin; Mapped by CNV

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Lionel, A. C., 2011	In one family, a 33kb de novo deletion at 4q31.3 was detected in a male proband (27696.3) with ADHD and anxiety traits who also exhibited seizure-like symptoms. The deletion eliminates two exons of the DCLK2 gene.	Trend

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Lionel[2011]_1	chr4:0-0 (NCBI36 / hg18)	33	4q31.3	Loss	D

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 5)

ID	Name	Type	No. of Genes in ADHDgene
GO:0004674	protein serine/threonine kinase activity	Molecular Function	61
GO:0005737	cytoplasm	Cellular Component	690
GO:0005524	ATP binding	Molecular Function	228
GO:0035556	intracellular signal transduction	Biological Process	44
GO:0005856	cytoskeleton	Cellular Component	54

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DCLK2 (count: 0)

Genes shared at least 2 KEGG pathways with DCLK2 (count: 0)

View in gBrowse

Region: chr4:150999426..151178609 View in gBrowse