ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	FLII
Symbol Alias	FLI, FLIL, Fli1, MGC39265
Approved Name	flightless I homolog (Drosophila)
Previous Name	flightless I (Drosophila) homolog
Location	17p11.2
Position	chr17:18148150-18162056, -
External Links	HGNC: 3750 Entrez Gene: 2314 Ensembl: ENSG00000177731 UCSC: uc002gsr.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
17p11	chr17:16000000-24000000	3 (2/0/1)

Gene related GO terms (count: 11)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003779	actin binding	Molecular Function		46
GO:0005737	cytoplasm	Cellular Component		690
GO:0005730	nucleolus	Cellular Component		243
GO:0005634	nucleus	Cellular Component		770
GO:0005515	protein binding	Molecular Function	IPI[10366446]	910
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0005813	centrosome	Cellular Component		71
GO:0005925	focal adhesion	Cellular Component		26
GO:0006936	muscle contraction	Biological Process	TAS[9177775]	18
GO:0007275	multicellular organismal development	Biological Process		71

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FLII (count: 48)

Gene Symbol	Pathway Count	Pathway List
AATF	6	cytoplasm; nucleolus; nucleus; protein binding; centrosome; focal adhesion;
CTNND2	6	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development;
DAXX	6	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
DPF2	6	cytoplasm; nucleolus; nucleus; transcription, DNA-dependent; regulation of transcription, DNA-dependent; centrosome;
HOXB1	6	cytoplasm; nucleolus; nucleus; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development;
LPXN	6	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent; focal adhesion;
MAPK1	6	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent; focal adhesion;
PSPC1	6	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
RFWD2	6	cytoplasm; nucleolus; nucleus; protein binding; centrosome; focal adhesion;
FHOD3	5	actin binding; cytoplasm; nucleolus; nucleus; protein binding;
KLHL20	5	actin binding; cytoplasm; nucleolus; nucleus; protein binding;
WASL	5	actin binding; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
APBB1	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
ATXN1	5	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
BCLAF1	5	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
CCDC85B	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; centrosome;
CDCA7L	5	cytoplasm; nucleolus; nucleus; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
CEP164	5	cytoplasm; nucleolus; nucleus; protein binding; centrosome;
CEP57	5	cytoplasm; nucleolus; nucleus; protein binding; centrosome;
CTNND1	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
DHX9	5	cytoplasm; nucleolus; nucleus; protein binding; centrosome;
GRHL1	5	cytoplasm; nucleus; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development;
GSK3B	5	cytoplasm; nucleolus; nucleus; protein binding; centrosome;
HABP4	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
HOXA9	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; multicellular organismal development;
ID2	5	cytoplasm; nucleolus; nucleus; protein binding; multicellular organismal development;
IGHMBP2	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
MEN1	5	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
PAFAH1B1	5	cytoplasm; nucleolus; nucleus; protein binding; centrosome;
POU2F3	5	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
PTPN14	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
RPS6KA4	5	cytoplasm; nucleolus; nucleus; protein binding; regulation of transcription, DNA-dependent;
RRP8	5	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
SAP18	5	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
SCAI	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
SSRP1	5	cytoplasm; nucleolus; nucleus; protein binding; regulation of transcription, DNA-dependent;
TCF25	5	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
TERF2IP	5	cytoplasm; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
TFAP2A	5	cytoplasm; nucleolus; nucleus; protein binding; centrosome;
XRCC5	5	cytoplasm; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
ZFR	5	cytoplasm; nucleolus; nucleus; protein binding; multicellular organismal development;
ZNF263	5	cytoplasm; nucleolus; nucleus; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
ZNF77	5	cytoplasm; nucleolus; nucleus; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
HINFP	5	nucleolus; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
INO80E	5	nucleolus; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
SETD1A	5	nucleolus; nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
ZNF74	5	nucleolus; nucleus; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development;
LMX1B	5	nucleus; protein binding; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development;

Genes shared at least 2 KEGG pathways with FLII (count: 0)

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Region: chr17:18148150..18162056 View in gBrowse