ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Region Report

Basic Info

Region Name	17p11
Chromosome Position	chr17:16000000-24000000
#studies (significant/non-significant/trend)	3(2/0/1)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result of Statistical Analysis
Ogdie MN, 2004	D17S947, D17S839, D17S953, D17S1857, D17S2196	multipoint MLS=3.63 (nominal P=0.000045, empiric P...... multipoint MLS=3.63 (nominal P=0.000045, empiric P=0.015) for marker D17S947; single-point MLS=1.84 (nominal P=0.0032) for marker D17S839; single-point MLS=1.23 (nominal P=0.014) for marker D17S953; single-point MLS=2.06 (nominal P=0.0019) for marker D17S1857; single-point MLS=1.7 (nominal P=0.0045) for marker D17S2196 More...	significant evidence of linkage significant evidence of linkage	Significant
Ogdie MN, 2003	D17S1857	Multipoint MLS Linkage Analysis: with marker D17S1857, MLS=0...... Multipoint MLS Linkage Analysis: with marker D17S1857, MLS=0.79 (P=0.02824) for wave 1, MLS=2.33 (P=0.00053) for wave 2, MLS=2.98 (P=0.00011) for combined; Single-Point MLS Linkage Analysis: with marker D17S1857, MLS=0.441 (P=0.07708) for wave 1, MLS=1.247 (P=0.00771) for wave 2, MLS=1.326 (P=0.00637) for combined More...	suggestive evidence suggestive evidence	Trend
Arcos-Burgos M, 2004 (a)	D17S799, D17S1876, D17S678, D17S1881, D17S1844, D17S1791	Linkage of genomewide scan: LOD=1.98, MLS=2.829, NPL=3 with ...... Linkage of genomewide scan: LOD=1.98, MLS=2.829, NPL=3 with marker D17S799; Family-specific linkage of fine mapping: LOD=3.4, NPL_all Z^b >12.0 with marker D17S1876;LOD=3.5, NPL_all Z^b >12.0 with marker D17S678;LOD=3.9, NPL_all Z^b >12.0 with marker D17S1881;LOD=3.8, NPL_all Z^b >12.0 with marker D17S1844;LOD=3.7, NPL_all Z^b >12.0 with marker D17S1791; Linkage of fine mapping in combined families: LOD=2.5, NPL_all Z^b >12.0 with marker D17S1876 More...	significant linkage significant linkage	Significant

Region related genes (count: 130)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
MAP2K3	mitogen-activated protein kinase kinase 3	17q11.2	1(0/1/0)

Genes from other sources (count: 129)

Approved Symbol	Approved Name	Location
PRPSAP2	phosphoribosyl pyrophosphate synthetase-associated protein 2	17p12-p11.2
GRAPL	GRB2-related adaptor protein-like	17p11.2
GRAP	GRB2-related adaptor protein	17p11.2
UPF3AP1	UPF3 regulator of nonsense transcripts homolog A (yeast) pseudogene 1	17p11.2
MIR1288	microRNA 1288	17
UPF3AP2	UPF3 regulator of nonsense transcripts homolog A (yeast) pseudogene 2	17p11.2
ULK2	unc-51-like kinase 2 (C. elegans)	17p11.2
USP22	ubiquitin specific peptidase 22	17p11.2
ALKBH5	alkB, alkylation repair homolog 5 (E. coli)	17p11.2
PLD6	phospholipase D family, member 6	17p11.2
MIR33B	microRNA 33b	17p11.2
DRG2	developmentally regulated GTP binding protein 2	17p13-p12
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	17p11.2
RPS28P9	ribosomal protein S28 pseudogene 9	17p11.1
ALDH3A2	aldehyde dehydrogenase 3 family, member A2	17p11.2
SRP68P3	signal recognition particle 68kDa pseudogene 3	17p11.2
RPS2P46	ribosomal protein S2 pseudogene 46	17p11
AKAP10	A kinase (PRKA) anchor protein 10	17p11.1
RPL7AP65	ribosomal protein L7a pseudogene 65	17p11.2
DHRS7B	dehydrogenase/reductase (SDR family) member 7B	17p12
FAM27L	family with sequence similarity 27-like	17p11.2
NEK4P2	NIMA (never in mitosis gene a)-related kinase 4 pseudogene 2	17p11.2
CCDC144NL	coiled-coil domain containing 144 family, N-terminal like	17p11.2
CCDC144C	coiled-coil domain containing 144C	17p11.2
CCDC144B	coiled-coil domain containing 144B	17p11.2
PEMT	phosphatidylethanolamine N-methyltransferase	17p11.2
CCDC144A	coiled-coil domain containing 144A	17p11.2
FAM18B1	family with sequence similarity 18, member B1	17p11.2
PIGL	phosphatidylinositol glycan anchor biosynthesis, class L	17p12-p11.2
SHMT1	serine hydroxymethyltransferase 1 (soluble)	17p11.2
MAPK7	mitogen-activated protein kinase 7	17p11.2
LLGL1	lethal giant larvae homolog 1 (Drosophila)	17p11.2
FAM108A7P	family with sequence similarity 108, member A7, pseudogene	17p11.2
FAM106CP	family with sequence similarity 106, member C, pseudogene	17p11.2
FAM106B	family with sequence similarity 106, member B	17p11.2
FAM106A	family with sequence similarity 106, member A	17p11.2
LRRC48	leucine rich repeat containing 48	17p11.2
TMEM11	transmembrane protein 11	17p11.1
NOS2P2	nitric oxide synthase 2 pseudogene 2	17p11.2
NOS2P3	nitric oxide synthase 2 pseudogene 3	17p11.2
MEIS3P2	Meis homeobox 3 pseudogene 2	17p11.2
RPL13P12	ribosomal protein L13 pseudogene 12	17p11.2
SCDP1	stearoyl-CoA desaturase (delta-9-desaturase) pseudogene 1	17p11.2
MFAP4	microfibrillar-associated protein 4	17p11.2
MIR1180	microRNA 1180	17
RPL17P43	ribosomal protein L17 pseudogene 43	17p11.2
NT5M	5',3'-nucleotidase, mitochondrial	17p11.2
EVPLL	envoplakin-like	17p11.2
CENPV	centromere protein V	17p11.2
EPN2	epsin 2	17p11.1
RPL21P120	ribosomal protein L21 pseudogene 120	17p11.2
RPL21P121	ribosomal protein L21 pseudogene 121	17p11.2
ZNF286B	zinc finger protein 286B	17p11.2
TBC1D28	TBC1 domain family, member 28	17p11.2
ZNF287	zinc finger protein 287	17p11.2
TBC1D27	TBC1 domain family, member 27	17p11.2
MED9	mediator complex subunit 9	17p11.2
CDRT15L2	CMT1A duplicated region transcript 15-like 2	17p11.2
KRT16P5	keratin 16 pseudogene 5	17p11.1
KRT16P4	keratin 16 pseudogene 4	17p11.2
KRT17P2	keratin 17 pseudogene 2	17p11.2
KRT17P1	keratin 17 pseudogene 1	17p11.2
KRT16P1	keratin 16 pseudogene 1	17p11.2
TRNAG26	transfer RNA glycine 26 (anticodon CCC)	17
KRT16P3	keratin 16 pseudogene 3	17p11.2
KRT16P2	keratin 16 pseudogene 2	17p11.2
FLII	flightless I homolog (Drosophila)	17p11.2
ATPAF2	ATP synthase mitochondrial F1 complex assembly factor 2	17p11.2
SMCR7	Smith-Magenis syndrome chromosome region, candidate 7	17p11.2
SMCR8	Smith-Magenis syndrome chromosome region, candidate 8	17p11.2
ZNF624	zinc finger protein 624	17p11.2
FLCN	folliculin	17p11.2
SMCR2	Smith-Magenis syndrome chromosome region, candidate 2 (non-protein coding)	17p11.2
SMCR5	Smith-Magenis syndrome chromosome region, candidate 5 (non-protein coding)	17p11.2
TRIM16L	tripartite motif containing 16-like	17p11.2
B9D1	B9 protein domain 1	17p11.2
COTL1P2	coactosin-like 1 (Dictyostelium) pseudogene 2	17p11.2
MYO15A	myosin XVA	17p11.2
FOXO3B	forkhead box O3B pseudogene	17p11
COTL1P1	coactosin-like 1 (Dictyostelium) pseudogene 1	17p11.2
SNORA59B	small nucleolar RNA, H/ACA box 59B	17p11.2
MTRNR2L1	MT-RNR2-like 1	17p11.2
COPS3	COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)	17p11.2
TOM1L2	target of myb1-like 2 (chicken)	17p11.2
FAM83G	family with sequence similarity 83, member G	17p11.2
NCRNA00188	non-protein coding RNA 188	17p11.2
LGALS9C	lectin, galactoside-binding, soluble, 9C	17p11.2
LGALS9B	lectin, galactoside-binding, soluble, 9B	17p11.2
NCOR1	nuclear receptor corepressor 1	17p11.2
TOP3A	topoisomerase (DNA) III alpha	17p12-p11.2
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	17p11.2
KYNUP3	kynureninase pseudogene 3	17p11.2
KYNUP2	kynureninase pseudogene 2	17p11.2
SLC47A2	solute carrier family 47, member 2	17p11.2
KYNUP1	kynureninase pseudogene 1	17p11.2
SLC47A1	solute carrier family 47, member 1	17p11.2
SLC5A10	solute carrier family 5 (sodium/glucose cotransporter), member 10	17p11.2
FBXW10	F-box and WD repeat domain containing 10	17p11
RNASEH1P2	ribonuclease H1 pseudogene 2	17p11.2
RNASEH1P1	ribonuclease H1 pseudogene 1	17p11.2
RNF112	ring finger protein 112	17p11.2
RASD1	RAS, dexamethasone-induced 1	17p11.2
UBBP4	ubiquitin B pseudogene 4	17p11.2
UBB	ubiquitin B	17p12-p11.2
RAI1	retinoic acid induced 1	17p11.2
SRP68P2	signal recognition particle 68kDa pseudogene 2	17p11.2
SRP68P1	signal recognition particle 68kDa pseudogene 1	17p11.2
SREBF1	sterol regulatory element binding transcription factor 1	17p11.2
SPECC1	sperm antigen with calponin homology and coiled-coil domains 1	17p11.2
MPRIP	myosin phosphatase Rho interacting protein	17p11.2
SNORD3A	small nucleolar RNA, C/D box 3A	17p11.2
SNORD3B-1	small nucleolar RNA, C/D box 3B-1	17p11.2
SNORD3B-2	small nucleolar RNA, C/D box 3B-2	17p11.2
SNORD3C	small nucleolar RNA, C/D box 3C	17p11.2
C17orf39	chromosome 17 open reading frame 39	17p11.2
C17orf51	chromosome 17 open reading frame 51	17p11.2
TRPV2	transient receptor potential cation channel, subfamily V, member 2	17p11.2
C17orf76	chromosome 17 open reading frame 76	17p11.2
KCNJ12	potassium inwardly-rectifying channel, subfamily J, member 12	17p11.1
TRNAW7	transfer RNA tryptophan 7 (anticodon CCA)	17
FTLP12	ferritin, light polypeptide pseudogene 12	17p11.2
FTLP13	ferritin, light polypeptide pseudogene 13	17p11.2
C17orf103	chromosome 17 open reading frame 103	17p11.2
TRNAS30P	transfer RNA serine 30 (anticodon UGA) pseudogene	17p11.2
TRNAQ41P	transfer RNA glutamine 41 (anticodon UUG) pseudogene	17p11.2
SNORD49B	small nucleolar RNA, C/D box 49B	17p11.2
SNORD65	small nucleolar RNA, C/D box 65	17p11.2
SNORD3D	small nucleolar RNA, C/D box 3D	17p11.2
SNORD49A	small nucleolar RNA, C/D box 49A	17p11.2

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Region: chr17:16000000..24000000 View in gBrowse