ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	BCLAF1
Symbol Alias	KIAA0164, BTF
Approved Name	BCL2-associated transcription factor 1
Location	6q22-q23
Position	chr6:136578001-136610989, -
External Links	HGNC: 16863 Entrez Gene: 9774 Ensembl: ENSG00000029363 UCSC: uc003qgx.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045892	negative regulation of transcription, DNA-dependent	Biological Process	IDA[10330179]; TAS[10330179]	64
GO:2000144	positive regulation of DNA-dependent transcription, initiation	Biological Process	IMP[17938203]	1
GO:2001022	positive regulation of response to DNA damage stimulus	Biological Process	IMP[17938203]	1
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	Biological Process	IMP[17938203]	2
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0006917	induction of apoptosis	Biological Process	TAS[10330179]	31
GO:0043065	positive regulation of apoptotic process	Biological Process	IDA[10330179]	34
GO:0043620	regulation of DNA-dependent transcription in response to stress	Biological Process	IMP[17938203]	1
GO:0005515	protein binding	Molecular Function	IPI[15009215]	910
GO:0005634	nucleus	Cellular Component		770
GO:0005730	nucleolus	Cellular Component		243
GO:0005737	cytoplasm	Cellular Component		690
GO:0003677	DNA binding	Molecular Function	IDA[10330179]	220

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with BCLAF1 (count: 51)

Gene Symbol	Pathway Count	Pathway List
ATXN1	7	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
DAXX	7	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; induction of apoptosis; protein binding; nucleus; nucleolus; cytoplasm;
MEN1	7	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of apoptotic process; protein binding; nucleus; nucleolus; cytoplasm;
XRCC5	7	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
MAPK1	7	transcription, DNA-dependent; induction of apoptosis; protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
HINFP	6	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; nucleolus; DNA binding;
RBPJ	6	negative regulation of transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
ZBTB16	6	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of apoptotic process; protein binding; nucleus; DNA binding;
ZNF263	6	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding;
TCF25	6	transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
BRMS1	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; cytoplasm;
CCDC85B	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; cytoplasm;
CREBZF	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; DNA binding;
ELK3	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; nucleolus;
GSK3B	5	negative regulation of transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
HES1	5	negative regulation of transcription, DNA-dependent; protein binding; nucleus; cytoplasm; DNA binding;
HMGA1	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; DNA binding;
HSPA8	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; nucleolus;
ID2	5	negative regulation of transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
KAT5	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; nucleolus;
MPHOSPH8	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; nucleolus; cytoplasm;
PDCD4	5	negative regulation of transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
RELA	5	negative regulation of transcription, DNA-dependent; protein binding; nucleus; cytoplasm; DNA binding;
TFAP2A	5	negative regulation of transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
ZNF24	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; DNA binding;
ZNF423	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein binding; nucleus; DNA binding;
PMAIP1	5	positive regulation of intrinsic apoptotic signaling pathway; induction of apoptosis; positive regulation of apoptotic process; protein binding; nucleus;
APBB1	5	transcription, DNA-dependent; positive regulation of apoptotic process; protein binding; nucleus; cytoplasm;
DPF2	5	transcription, DNA-dependent; induction of apoptosis; nucleus; nucleolus; cytoplasm;
ETS1	5	transcription, DNA-dependent; induction of apoptosis; protein binding; nucleus; DNA binding;
FLII	5	transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
HOXA5	5	transcription, DNA-dependent; positive regulation of apoptotic process; protein binding; nucleus; DNA binding;
HOXB1	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding;
IGHMBP2	5	transcription, DNA-dependent; protein binding; nucleus; cytoplasm; DNA binding;
NCOR2	5	transcription, DNA-dependent; protein binding; nucleus; nucleolus; DNA binding;
NPAS3	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding;
POU2F3	5	transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
PSPC1	5	transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
RRP8	5	transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
SAP18	5	transcription, DNA-dependent; protein binding; nucleus; nucleolus; cytoplasm;
ZNF367	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding;
ZNF77	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding;
PYCARD	5	induction of apoptosis; positive regulation of apoptotic process; protein binding; nucleus; cytoplasm;
WWOX	5	induction of apoptosis; positive regulation of apoptotic process; protein binding; nucleus; cytoplasm;
RAD9A	5	positive regulation of apoptotic process; protein binding; nucleus; nucleolus; cytoplasm;
CHD1L	5	protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
DHX9	5	protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
FUS	5	protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
PGR	5	protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
SSRP1	5	protein binding; nucleus; nucleolus; cytoplasm; DNA binding;
ZFR	5	protein binding; nucleus; nucleolus; cytoplasm; DNA binding;

Genes shared at least 2 KEGG pathways with BCLAF1 (count: 0)

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Region: chr6:136578001..136610989 View in gBrowse