ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	BCLAF1
Symbol Alias	KIAA0164, BTF
Approved Name	BCL2-associated transcription factor 1
Location	6q22-q23
Position	chr6:136578001-136610989, -1
External Links	HGNC: 16863 Entrez Gene: 9774 Ensembl: ENSG00000029363 UCSC: uc003qgx.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005737	cytoplasm	cellular component	IEA	781
GO:0043065	positive regulation of apoptotic process	biological process	IDA[10330179]	38
GO:2001022	positive regulation of response to DNA damage stimulus	biological process	IMP[17938203]	1
GO:0006917	induction of apoptosis	biological process	TAS[10330179]	35
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	biological process	IMP[17938203]	3
GO:0006351	transcription, DNA-dependent	biological process	IEA	281
GO:0045892	negative regulation of transcription, DNA-dependent	biological process	IDA[10330179]; TAS[10330179]	77
GO:0005515	protein binding	molecular function	IPI[15009215]	1015
GO:0003677	DNA binding	molecular function	IDA[10330179]	257
GO:0043620	regulation of DNA-dependent transcription in response to stress	biological process	IMP[17938203]	1
GO:0005730	nucleolus	cellular component	IDA; IDA	271
GO:0005634	nucleus	cellular component	IDA; NAS	877
GO:2000144	positive regulation of DNA-dependent transcription, initiation	biological process	IMP[17938203]	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with BCLAF1 (count: 55)

Gene Symbol	Pathway Count	Pathway List
DAXX	7	cytoplasm; induction of apoptosis; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
MEN1	7	cytoplasm; positive regulation of apoptotic process; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
XRCC5	7	cytoplasm; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleolus; nucleus;
ATXN1	7	cytoplasm; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleolus; nucleus;
MAPK1	7	cytoplasm; induction of apoptosis; transcription, DNA-dependent; protein binding; DNA binding; nucleolus; nucleus;
ZNF263	6	cytoplasm; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; DNA binding; nucleolus; nucleus;
TCF25	6	cytoplasm; transcription, DNA-dependent; protein binding; DNA binding; nucleolus; nucleus;
RBPJ	6	cytoplasm; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleolus; nucleus;
ZBTB16	6	positive regulation of apoptotic process; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleus;
HINFP	6	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleolus; nucleus;
DHX9	5	cytoplasm; protein binding; DNA binding; nucleolus; nucleus;
RRP8	5	cytoplasm; transcription, DNA-dependent; protein binding; nucleolus; nucleus;
PNN	5	cytoplasm; transcription, DNA-dependent; DNA binding; nucleolus; nucleus;
RAD9A	5	cytoplasm; positive regulation of apoptotic process; protein binding; nucleolus; nucleus;
SSRP1	5	cytoplasm; protein binding; DNA binding; nucleolus; nucleus;
ZNF77	5	cytoplasm; transcription, DNA-dependent; DNA binding; nucleolus; nucleus;
BRMS1	5	cytoplasm; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; nucleus;
POU2F3	5	cytoplasm; transcription, DNA-dependent; protein binding; nucleolus; nucleus;
RELA	5	cytoplasm; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleus;
CHD1L	5	cytoplasm; protein binding; DNA binding; nucleolus; nucleus;
FLII	5	cytoplasm; transcription, DNA-dependent; protein binding; nucleolus; nucleus;
ZNF367	5	cytoplasm; transcription, DNA-dependent; DNA binding; nucleolus; nucleus;
FUS	5	cytoplasm; protein binding; DNA binding; nucleolus; nucleus;
PSPC1	5	cytoplasm; transcription, DNA-dependent; protein binding; nucleolus; nucleus;
HES1	5	cytoplasm; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleus;
PYCARD	5	cytoplasm; positive regulation of apoptotic process; induction of apoptosis; protein binding; nucleus;
HOXB1	5	cytoplasm; transcription, DNA-dependent; DNA binding; nucleolus; nucleus;
DPF2	5	cytoplasm; induction of apoptosis; transcription, DNA-dependent; nucleolus; nucleus;
ZNF174	5	cytoplasm; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; nucleolus; nucleus;
MPHOSPH8	5	cytoplasm; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; nucleolus; nucleus;
IGHMBP2	5	cytoplasm; transcription, DNA-dependent; protein binding; DNA binding; nucleus;
NPAS3	5	cytoplasm; transcription, DNA-dependent; DNA binding; nucleolus; nucleus;
ID2	5	cytoplasm; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
PDCD4	5	cytoplasm; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
WWOX	5	cytoplasm; positive regulation of apoptotic process; induction of apoptosis; protein binding; nucleus;
GSK3B	5	cytoplasm; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
ZFR	5	cytoplasm; protein binding; DNA binding; nucleolus; nucleus;
SOX8	5	cytoplasm; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; DNA binding; nucleus;
APBB1	5	cytoplasm; positive regulation of apoptotic process; transcription, DNA-dependent; protein binding; nucleus;
PGR	5	cytoplasm; protein binding; DNA binding; nucleolus; nucleus;
SAP18	5	cytoplasm; transcription, DNA-dependent; protein binding; nucleolus; nucleus;
CCDC85B	5	cytoplasm; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; nucleus;
PMAIP1	5	positive regulation of apoptotic process; induction of apoptosis; positive regulation of intrinsic apoptotic signaling pathway; protein binding; nucleus;
HOXA5	5	positive regulation of apoptotic process; transcription, DNA-dependent; protein binding; DNA binding; nucleus;
TFAP4	5	positive regulation of apoptotic process; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleus;
ETS1	5	induction of apoptosis; transcription, DNA-dependent; protein binding; DNA binding; nucleus;
KAT5	5	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
GATAD2A	5	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
ZNF24	5	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleus;
CREBZF	5	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleus;
ZNF423	5	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleus;
ELK3	5	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
HSPA8	5	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; nucleolus; nucleus;
HMGA1	5	transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; protein binding; DNA binding; nucleus;
NCOR2	5	transcription, DNA-dependent; protein binding; DNA binding; nucleolus; nucleus;

Genes shared at least 2 KEGG pathways with BCLAF1 (count: 0)

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Region: chr6:136578001..136610989 View in gBrowse