ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DPF2
Previous Symbol	REQ
Symbol Alias	ubi-d4
Approved Name	D4, zinc and double PHD fingers family 2
Previous Name	requiem, apoptosis response zinc finger gene
Location	11q13.1
Position	chr11:65101225-65120720, +
External Links	HGNC: 9964 Entrez Gene: 5977 Ensembl: ENSG00000133884 UCSC: uc001odm.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0005737	cytoplasm	Cellular Component		690
GO:0005813	centrosome	Cellular Component		71
GO:0005634	nucleus	Cellular Component		770
GO:0005730	nucleolus	Cellular Component		243
GO:0043231	intracellular membrane-bounded organelle	Cellular Component		62
GO:0097190	apoptotic signaling pathway	Biological Process	TAS[7961935]	6
GO:0006917	induction of apoptosis	Biological Process	TAS[8812431]	31
GO:0008270	zinc ion binding	Molecular Function		323

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DPF2 (count: 25)

Gene Symbol	Pathway Count	Pathway List
DAXX	6	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; nucleolus; induction of apoptosis;
FLII	6	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; centrosome; nucleus; nucleolus;
TRIM22	6	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; intracellular membrane-bounded organelle; zinc ion binding;
ZNF263	6	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; nucleolus; zinc ion binding;
ZNF77	6	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; nucleolus; zinc ion binding;
ATXN1	5	transcription, DNA-dependent; cytoplasm; nucleus; nucleolus; intracellular membrane-bounded organelle;
BCL11A	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; zinc ion binding;
BCLAF1	5	transcription, DNA-dependent; cytoplasm; nucleus; nucleolus; induction of apoptosis;
CDCA7L	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; nucleolus;
HINFP	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; nucleus; nucleolus; zinc ion binding;
HOXB1	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; nucleolus;
IGHMBP2	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; zinc ion binding;
LPXN	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; zinc ion binding;
MAPK1	5	transcription, DNA-dependent; cytoplasm; nucleus; nucleolus; induction of apoptosis;
PSPC1	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytoplasm; nucleus; nucleolus;
SF1	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; nucleus; nucleolus; zinc ion binding;
ZBTB34	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; nucleus; nucleolus; zinc ion binding;
ZBTB9	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; nucleus; nucleolus; zinc ion binding;
ZNF367	5	transcription, DNA-dependent; cytoplasm; nucleus; nucleolus; zinc ion binding;
ZNF74	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; nucleus; nucleolus; zinc ion binding;
MTA3	5	cytoplasm; nucleus; nucleolus; intracellular membrane-bounded organelle; zinc ion binding;
PGR	5	cytoplasm; nucleus; nucleolus; intracellular membrane-bounded organelle; zinc ion binding;
RFWD2	5	cytoplasm; centrosome; nucleus; nucleolus; zinc ion binding;
SLU7	5	cytoplasm; nucleus; nucleolus; intracellular membrane-bounded organelle; zinc ion binding;
TFAP2A	5	cytoplasm; centrosome; nucleus; nucleolus; intracellular membrane-bounded organelle;

Genes shared at least 2 KEGG pathways with DPF2 (count: 0)

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Region: chr11:65101225..65120720 View in gBrowse