ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TCF25
Symbol Alias	Nulp1, KIAA1049
Approved Name	transcription factor 25 (basic helix-loop-helix)
Location	16q24.3
Position	chr16:89940000-89977792, 1
External Links	HGNC: 29181 Entrez Gene: 22980 Ensembl: ENSG00000141002 UCSC: uc002fpb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	biological process	IDA[16574069]	90
GO:0007507	heart development	biological process	NAS[16574069]	29
GO:0003677	DNA binding	molecular function	IEA	257
GO:0005730	nucleolus	cellular component	IDA	271
GO:0003700	sequence-specific DNA binding transcription factor activity	molecular function	IDA[16574069]	148
GO:0005737	cytoplasm	cellular component	IDA	781
GO:0005634	nucleus	cellular component	IDA[16574069]	877
GO:0005515	protein binding	molecular function	IPI[19060904]	1015
GO:0006351	transcription, DNA-dependent	biological process	IEA	281
GO:0005739	mitochondrion	cellular component	IDA	221

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TCF25 (count: 77)

Gene Symbol	Pathway Count	Pathway List
RBPJ	7	negative regulation of transcription from RNA polymerase II promoter; DNA binding; nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding;
MAPK1	7	DNA binding; nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent; mitochondrion;
MEN1	6	negative regulation of transcription from RNA polymerase II promoter; nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
E4F1	6	negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; cytoplasm; protein binding; transcription, DNA-dependent;
IKZF1	6	negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
HNF1B	6	negative regulation of transcription from RNA polymerase II promoter; DNA binding; nucleolus; sequence-specific DNA binding transcription factor activity; nucleus; protein binding;
SREBF1	6	negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
HES1	6	negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding;
ZNF174	6	negative regulation of transcription from RNA polymerase II promoter; nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
NCOR2	6	negative regulation of transcription from RNA polymerase II promoter; DNA binding; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
ATXN1	6	DNA binding; nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
XRCC5	6	DNA binding; nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
HOXB1	6	DNA binding; nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
ZNF263	6	DNA binding; nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
BCLAF1	6	DNA binding; nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
HINFP	6	DNA binding; nucleolus; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
ZNF367	6	DNA binding; nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
POU2F3	6	nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
ELK3	6	nucleolus; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent; mitochondrion;
NEDD4L	5	negative regulation of transcription from RNA polymerase II promoter; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
CRYM	5	negative regulation of transcription from RNA polymerase II promoter; nucleolus; cytoplasm; nucleus; mitochondrion;
KAT5	5	negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
ZNF205	5	negative regulation of transcription from RNA polymerase II promoter; DNA binding; nucleus; protein binding; transcription, DNA-dependent;
IRF7	5	negative regulation of transcription from RNA polymerase II promoter; DNA binding; cytoplasm; nucleus; protein binding;
HEY2	5	negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding;
TFAP2B	5	negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; protein binding;
RNF2	5	negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; protein binding; transcription, DNA-dependent;
KDM1A	5	negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
AHRR	5	negative regulation of transcription from RNA polymerase II promoter; DNA binding; cytoplasm; nucleus; transcription, DNA-dependent;
CREBBP	5	negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding;
DRAP1	5	negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent;
MYB	5	negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding; transcription, DNA-dependent;
CHCHD3	5	negative regulation of transcription from RNA polymerase II promoter; cytoplasm; nucleus; protein binding; mitochondrion;
ID2	5	negative regulation of transcription from RNA polymerase II promoter; nucleolus; cytoplasm; nucleus; protein binding;
HOXA2	5	negative regulation of transcription from RNA polymerase II promoter; nucleolus; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent;
PRDM1	5	negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
MTA2	5	negative regulation of transcription from RNA polymerase II promoter; nucleolus; sequence-specific DNA binding transcription factor activity; nucleus; protein binding;
KANK2	5	negative regulation of transcription from RNA polymerase II promoter; cytoplasm; protein binding; transcription, DNA-dependent; mitochondrion;
ZNF189	5	negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent;
STRN3	5	negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding;
TBX1	5	heart development; DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent;
TH	5	heart development; cytoplasm; nucleus; protein binding; mitochondrion;
FUS	5	DNA binding; nucleolus; cytoplasm; nucleus; protein binding;
ZNF24	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
FEN1	5	DNA binding; nucleolus; nucleus; protein binding; mitochondrion;
ZBTB9	5	DNA binding; nucleolus; nucleus; transcription, DNA-dependent; mitochondrion;
NPAS3	5	DNA binding; nucleolus; cytoplasm; nucleus; transcription, DNA-dependent;
SOX8	5	DNA binding; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
HOXA5	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
TAF13	5	DNA binding; nucleolus; sequence-specific DNA binding transcription factor activity; nucleus; protein binding;
ZNF396	5	DNA binding; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
IGHMBP2	5	DNA binding; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
ZFR	5	DNA binding; nucleolus; cytoplasm; nucleus; protein binding;
CHD1L	5	DNA binding; nucleolus; cytoplasm; nucleus; protein binding;
ZNF397	5	DNA binding; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
PNN	5	DNA binding; nucleolus; cytoplasm; nucleus; transcription, DNA-dependent;
PGR	5	DNA binding; nucleolus; cytoplasm; nucleus; protein binding;
ZNF77	5	DNA binding; nucleolus; cytoplasm; nucleus; transcription, DNA-dependent;
TAF4B	5	DNA binding; nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus;
CREBZF	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
RELA	5	DNA binding; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding;
HMGA1	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
ETS1	5	DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
DHX9	5	DNA binding; nucleolus; cytoplasm; nucleus; protein binding;
SSRP1	5	DNA binding; nucleolus; cytoplasm; nucleus; protein binding;
AATF	5	nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding;
ZEB2	5	nucleolus; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription, DNA-dependent;
STAP1	5	nucleolus; cytoplasm; nucleus; protein binding; mitochondrion;
RRP8	5	nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
FLII	5	nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
DCPS	5	nucleolus; cytoplasm; nucleus; protein binding; mitochondrion;
GATAD2A	5	nucleolus; sequence-specific DNA binding transcription factor activity; nucleus; protein binding; transcription, DNA-dependent;
PSPC1	5	nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
SAP18	5	nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
DAXX	5	nucleolus; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
MKL2	5	sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;
HOXA9	5	sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; protein binding; transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with TCF25 (count: 0)

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Region: chr16:89940000..89977792 View in gBrowse