ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TCF25
Symbol Alias	Nulp1, KIAA1049
Approved Name	transcription factor 25 (basic helix-loop-helix)
Location	16q24.3
Position	chr16:89939970-89977792, +
External Links	HGNC: 29181 Entrez Gene: 22980 Ensembl: ENSG00000141002 UCSC: uc002fpb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0007507	heart development	Biological Process	NAS[16574069]	23
GO:0005634	nucleus	Cellular Component	IDA[16574069]	770
GO:0005730	nucleolus	Cellular Component		243
GO:0005737	cytoplasm	Cellular Component		690
GO:0005739	mitochondrion	Cellular Component		183
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[16574069]	78
GO:0003677	DNA binding	Molecular Function		220
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	IDA[16574069]	132
GO:0005515	protein binding	Molecular Function	IPI[19060904]	910

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TCF25 (count: 69)

Gene Symbol	Pathway Count	Pathway List
MAPK1	7	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; mitochondrion; DNA binding; protein binding;
RBPJ	7	nucleus; nucleolus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
ATXN1	6	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding; protein binding;
BCLAF1	6	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding; protein binding;
ELK3	6	transcription, DNA-dependent; nucleus; nucleolus; mitochondrion; sequence-specific DNA binding transcription factor activity; protein binding;
HINFP	6	transcription, DNA-dependent; nucleus; nucleolus; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
HOXB1	6	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding; sequence-specific DNA binding transcription factor activity;
IKZF1	6	transcription, DNA-dependent; nucleus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity;
MEN1	6	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; protein binding;
NCOR1	6	transcription, DNA-dependent; nucleus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; protein binding;
NCOR2	6	transcription, DNA-dependent; nucleus; nucleolus; negative regulation of transcription from RNA polymerase II promoter; DNA binding; protein binding;
POU2F3	6	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; sequence-specific DNA binding transcription factor activity; protein binding;
SREBF1	6	transcription, DNA-dependent; nucleus; negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
XRCC5	6	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding; protein binding;
ZNF263	6	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding; sequence-specific DNA binding transcription factor activity;
ZNF367	6	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding; sequence-specific DNA binding transcription factor activity;
HES1	6	nucleus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
HNF1B	6	nucleus; nucleolus; negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
CREBZF	5	transcription, DNA-dependent; nucleus; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
DAXX	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; protein binding;
DRAP1	5	transcription, DNA-dependent; nucleus; negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity;
E2F5	5	transcription, DNA-dependent; cytoplasm; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
ETS1	5	transcription, DNA-dependent; nucleus; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
FLII	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; protein binding;
HMGA1	5	transcription, DNA-dependent; nucleus; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
HOXA2	5	transcription, DNA-dependent; nucleus; nucleolus; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity;
HOXA5	5	transcription, DNA-dependent; nucleus; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
HOXA9	5	transcription, DNA-dependent; nucleus; cytoplasm; sequence-specific DNA binding transcription factor activity; protein binding;
IGHMBP2	5	transcription, DNA-dependent; nucleus; cytoplasm; DNA binding; protein binding;
KANK2	5	transcription, DNA-dependent; cytoplasm; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; protein binding;
KAT5	5	transcription, DNA-dependent; nucleus; nucleolus; negative regulation of transcription from RNA polymerase II promoter; protein binding;
KDM1A	5	transcription, DNA-dependent; nucleus; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; protein binding;
MYB	5	transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
NEDD4L	5	transcription, DNA-dependent; nucleus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; protein binding;
NPAS3	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding;
PRDM1	5	transcription, DNA-dependent; nucleus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity;
PSPC1	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; protein binding;
RNF2	5	transcription, DNA-dependent; nucleus; nucleolus; negative regulation of transcription from RNA polymerase II promoter; protein binding;
RRP8	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; protein binding;
SAP18	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; protein binding;
TBX1	5	transcription, DNA-dependent; heart development; nucleus; DNA binding; sequence-specific DNA binding transcription factor activity;
ZBTB9	5	transcription, DNA-dependent; nucleus; nucleolus; mitochondrion; DNA binding;
ZNF189	5	transcription, DNA-dependent; nucleus; negative regulation of transcription from RNA polymerase II promoter; DNA binding; sequence-specific DNA binding transcription factor activity;
ZNF24	5	transcription, DNA-dependent; nucleus; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
ZNF396	5	transcription, DNA-dependent; nucleus; cytoplasm; DNA binding; sequence-specific DNA binding transcription factor activity;
ZNF397	5	transcription, DNA-dependent; nucleus; cytoplasm; DNA binding; sequence-specific DNA binding transcription factor activity;
ZNF77	5	transcription, DNA-dependent; nucleus; nucleolus; cytoplasm; DNA binding;
TH	5	heart development; nucleus; cytoplasm; mitochondrion; protein binding;
AATF	5	nucleus; nucleolus; cytoplasm; sequence-specific DNA binding transcription factor activity; protein binding;
CHCHD3	5	nucleus; cytoplasm; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; protein binding;
CHD1L	5	nucleus; nucleolus; cytoplasm; DNA binding; protein binding;
CRYM	5	nucleus; nucleolus; cytoplasm; mitochondrion; negative regulation of transcription from RNA polymerase II promoter;
DCPS	5	nucleus; nucleolus; cytoplasm; mitochondrion; protein binding;
DHX9	5	nucleus; nucleolus; cytoplasm; DNA binding; protein binding;
FEN1	5	nucleus; nucleolus; mitochondrion; DNA binding; protein binding;
FUS	5	nucleus; nucleolus; cytoplasm; DNA binding; protein binding;
HEY2	5	nucleus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; protein binding;
ID2	5	nucleus; nucleolus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; protein binding;
IRF7	5	nucleus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; DNA binding; protein binding;
MTA2	5	nucleus; nucleolus; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; protein binding;
PGR	5	nucleus; nucleolus; cytoplasm; DNA binding; protein binding;
RELA	5	nucleus; cytoplasm; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
SSRP1	5	nucleus; nucleolus; cytoplasm; DNA binding; protein binding;
STAP1	5	nucleus; nucleolus; cytoplasm; mitochondrion; protein binding;
STRN3	5	nucleus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; protein binding;
TAF13	5	nucleus; nucleolus; DNA binding; sequence-specific DNA binding transcription factor activity; protein binding;
TAF4B	5	nucleus; nucleolus; cytoplasm; DNA binding; sequence-specific DNA binding transcription factor activity;
TFAP2A	5	nucleus; nucleolus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; protein binding;
ZFR	5	nucleus; nucleolus; cytoplasm; DNA binding; protein binding;

Genes shared at least 2 KEGG pathways with TCF25 (count: 0)

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Region: chr16:89939970..89977792 View in gBrowse