ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CRYM
Symbol Alias	DFNA40
Approved Name	crystallin, mu
Location	16p
Position	chr16:21269839-21314404, -
External Links	HGNC: 2418 Entrez Gene: 1428 Ensembl: ENSG00000103316 UCSC: uc002dik.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16p12.3-12.2	chr16:16800000-24200000	1 (1/0/0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IMP[11897713]	78
GO:0003714	transcription corepressor activity	Molecular Function	IMP[11897713]	29
GO:0050661	NADP binding	Molecular Function	IDA[17242435]	6
GO:0047127	thiomorpholine-carboxylate dehydrogenase activity	Molecular Function		1
GO:0070327	thyroid hormone transport	Biological Process	IMP[11897713]	1
GO:0070324	thyroid hormone binding	Molecular Function	IDA[9328354]; IMP[16740909]	1
GO:0007605	sensory perception of sound	Biological Process	IMP[12471561]	31
GO:0005886	plasma membrane	Cellular Component		772
GO:0042803	protein homodimerization activity	Molecular Function	IDA[12590647]	113
GO:0042403	thyroid hormone metabolic process	Biological Process		1
GO:0005730	nucleolus	Cellular Component		243
GO:0005634	nucleus	Cellular Component		770
GO:0005739	mitochondrion	Cellular Component		183
GO:0005737	cytoplasm	Cellular Component		690

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CRYM (count: 8)

Gene Symbol	Pathway Count	Pathway List
TFAP2A	6	negative regulation of transcription from RNA polymerase II promoter; sensory perception of sound; protein homodimerization activity; nucleolus; nucleus; cytoplasm;
PDE2A	5	negative regulation of transcription from RNA polymerase II promoter; plasma membrane; protein homodimerization activity; nucleus; cytoplasm;
TCF25	5	negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; mitochondrion; cytoplasm;
SAP18	5	transcription corepressor activity; plasma membrane; nucleolus; nucleus; cytoplasm;
CRYAB	5	plasma membrane; protein homodimerization activity; nucleus; mitochondrion; cytoplasm;
KLHL7	5	plasma membrane; protein homodimerization activity; nucleolus; nucleus; cytoplasm;
PERP	5	plasma membrane; nucleolus; nucleus; mitochondrion; cytoplasm;
RNF40	5	plasma membrane; protein homodimerization activity; nucleolus; nucleus; cytoplasm;

Genes shared at least 2 KEGG pathways with CRYM (count: 0)

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Region: chr16:21269839..21314404 View in gBrowse