ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	GRHL1
Previous Symbol	TFCP2L2
Symbol Alias	LBP-32, MGR
Approved Name	grainyhead-like 1 (Drosophila)
Previous Name	transcription factor CP2-like 2
Location	2p25.2
Position	chr2:10091792-10142412, +
External Links	HGNC: 17923 Entrez Gene: 29841 Ensembl: ENSG00000134317 UCSC: uc002raa.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2p25.1	chr2:7100000-12200000	2 (1/0/1)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)

ID	Name	Type	No. of Genes in ADHDgene
GO:0003677	DNA binding	Molecular Function	220
GO:0005654	nucleoplasm	Cellular Component	183
GO:0005634	nucleus	Cellular Component	770
GO:0044255	cellular lipid metabolic process	Biological Process	30
GO:0007275	multicellular organismal development	Biological Process	71
GO:0044281	small molecule metabolic process	Biological Process	248
GO:0005794	Golgi apparatus	Cellular Component	157
GO:0005737	cytoplasm	Cellular Component	690
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	158
GO:0006351	transcription, DNA-dependent	Biological Process	247

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GRHL1 (count: 24)

Gene Symbol	Pathway Count	Pathway List
HOXB1	6	DNA binding; nucleus; multicellular organismal development; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
MAPK1	6	DNA binding; nucleoplasm; nucleus; Golgi apparatus; cytoplasm; transcription, DNA-dependent;
NCOR2	6	DNA binding; nucleoplasm; nucleus; cellular lipid metabolic process; small molecule metabolic process; transcription, DNA-dependent;
SCYL1	6	DNA binding; nucleus; Golgi apparatus; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
NCOR1	6	nucleoplasm; nucleus; cellular lipid metabolic process; small molecule metabolic process; cytoplasm; transcription, DNA-dependent;
SMARCD3	6	nucleoplasm; nucleus; cellular lipid metabolic process; small molecule metabolic process; cytoplasm; transcription, DNA-dependent;
ATXN1	5	DNA binding; nucleoplasm; nucleus; cytoplasm; transcription, DNA-dependent;
BANP	5	DNA binding; nucleus; multicellular organismal development; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
HINFP	5	DNA binding; nucleoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
HMGA1	5	DNA binding; nucleoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
IGHMBP2	5	DNA binding; nucleus; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
RREB1	5	DNA binding; nucleus; multicellular organismal development; cytoplasm; regulation of transcription, DNA-dependent;
SSRP1	5	DNA binding; nucleoplasm; nucleus; cytoplasm; regulation of transcription, DNA-dependent;
TAF4B	5	DNA binding; nucleoplasm; nucleus; cytoplasm; regulation of transcription, DNA-dependent;
XRCC5	5	DNA binding; nucleoplasm; nucleus; cytoplasm; transcription, DNA-dependent;
ZNF263	5	DNA binding; nucleus; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
ZNF521	5	DNA binding; nucleus; multicellular organismal development; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
ZNF74	5	DNA binding; nucleus; multicellular organismal development; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
ZNF77	5	DNA binding; nucleus; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
TERF2IP	5	nucleoplasm; nucleus; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
CTNND2	5	nucleus; multicellular organismal development; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
FLII	5	nucleus; multicellular organismal development; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;
LPIN1	5	nucleus; cellular lipid metabolic process; small molecule metabolic process; cytoplasm; transcription, DNA-dependent;
TRIM22	5	nucleus; Golgi apparatus; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with GRHL1 (count: 0)

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Region: chr2:10091792..10142412 View in gBrowse