ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SCYL1
Previous Symbol	NTKL
Symbol Alias	HT019, P105, GKLP, NKTL, TAPK, TRAP, TEIF, MGC78454
Approved Name	SCY1-like 1 (S. cerevisiae)
Previous Name	N-terminal kinase-like
Name Alias	teratoma-associated tyrosine kinase, "telomerase transcriptional elements-interacting factor", "telomerase regulation-associated protein"
Location	11q11-q12
Position	chr11:65292548-65306182, +
External Links	HGNC: 14372 Entrez Gene: 57410 Ensembl: ENSG00000142186 UCSC: uc001oea.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004713	protein tyrosine kinase activity	Molecular Function	NAS[10843802]	10
GO:0003677	DNA binding	Molecular Function		220
GO:0005524	ATP binding	Molecular Function		228
GO:0005634	nucleus	Cellular Component		770
GO:0005737	cytoplasm	Cellular Component	ISS[12783284]	690
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	Cellular Component	IDA[18556652]	17
GO:0005794	Golgi apparatus	Cellular Component	IDA[18556652]	157
GO:0005801	cis-Golgi network	Cellular Component	IDA[18556652]	14
GO:0005815	microtubule organizing center	Cellular Component		19
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	Biological Process	IDA[18556652]	16
GO:0030126	COPI vesicle coat	Cellular Component	IDA[18556652]	8

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SCYL1 (count: 11)

Gene Symbol	Pathway Count	Pathway List
MAPK1	7	DNA binding; ATP binding; nucleus; cytoplasm; Golgi apparatus; microtubule organizing center; transcription, DNA-dependent;
GRHL1	6	DNA binding; nucleus; cytoplasm; Golgi apparatus; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
IGHMBP2	6	DNA binding; ATP binding; nucleus; cytoplasm; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
YES1	5	protein tyrosine kinase activity; ATP binding; cytoplasm; Golgi apparatus; microtubule organizing center;
HOXB1	5	DNA binding; nucleus; cytoplasm; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
SRCAP	5	DNA binding; ATP binding; nucleus; Golgi apparatus; transcription, DNA-dependent;
XRCC5	5	DNA binding; ATP binding; nucleus; cytoplasm; transcription, DNA-dependent;
ZNF263	5	DNA binding; nucleus; cytoplasm; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
ZNF77	5	DNA binding; nucleus; cytoplasm; transcription, DNA-dependent; regulation of transcription, DNA-dependent;
COG3	5	nucleus; cytoplasm; Golgi apparatus; cis-Golgi network; retrograde vesicle-mediated transport, Golgi to ER;
TRIM22	5	nucleus; cytoplasm; Golgi apparatus; transcription, DNA-dependent; regulation of transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with SCYL1 (count: 0)

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Region: chr11:65292548..65306182 View in gBrowse