ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RREB1
Symbol Alias	HNT
Approved Name	ras responsive element binding protein 1
Name Alias	hindsight homolog (drosophila)
Location	6p25
Position	chr6:7107830-7252213, +
External Links	HGNC: 10449 Entrez Gene: 6239 Ensembl: ENSG00000124782 UCSC: uc003mxb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_78	chr6:6859406-7198730 (NCBI Build 35 (hg17))	339325	6p25.1-6p24.3	Duplication	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0003677	DNA binding	Molecular Function		220
GO:0005737	cytoplasm	Cellular Component	TAS[9305772]	690
GO:0005634	nucleus	Cellular Component	TAS[9305772]	770
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	TAS[8816445]	62
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	TAS[9305772]	158
GO:0007275	multicellular organismal development	Biological Process	TAS[8816445]	71
GO:0007265	Ras protein signal transduction	Biological Process	TAS[8816445]	15
GO:0008270	zinc ion binding	Molecular Function		323
GO:0016604	nuclear body	Cellular Component	TAS[9305772]	4
GO:0016607	nuclear speck	Cellular Component		34
GO:0045892	negative regulation of transcription, DNA-dependent	Biological Process		64
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	TAS[9305772]	80

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RREB1 (count: 51)

Gene Symbol	Pathway Count	Pathway List
HINFP	7	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; zinc ion binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
ZNF263	7	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; regulation of transcription, DNA-dependent; zinc ion binding; negative regulation of transcription, DNA-dependent;
ZBTB16	7	DNA binding; nucleus; zinc ion binding; nuclear body; nuclear speck; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
HMGA1	6	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
HOXB1	6	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; regulation of transcription, DNA-dependent; multicellular organismal development;
LHX1	6	sequence-specific DNA binding transcription factor activity; nucleus; transcription from RNA polymerase II promoter; zinc ion binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
RELA	6	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
TAF4B	6	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent;
TRIM22	6	sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; regulation of transcription, DNA-dependent; zinc ion binding; nuclear speck;
CBL	5	sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; regulation of transcription, DNA-dependent; zinc ion binding;
CREB5	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription from RNA polymerase II promoter; zinc ion binding; positive regulation of transcription, DNA-dependent;
EBF1	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; multicellular organismal development; positive regulation of transcription, DNA-dependent;
ETS1	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent;
FOXE1	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
FOXL1	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; multicellular organismal development;
FOXP2	5	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; zinc ion binding; negative regulation of transcription, DNA-dependent;
GATA6	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription from RNA polymerase II promoter; zinc ion binding; negative regulation of transcription, DNA-dependent;
HES1	5	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; negative regulation of transcription, DNA-dependent;
IKZF1	5	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; zinc ion binding;
KLF4	5	sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter; zinc ion binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
LMX1B	5	sequence-specific DNA binding transcription factor activity; nucleus; regulation of transcription, DNA-dependent; multicellular organismal development; zinc ion binding;
MLL	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription from RNA polymerase II promoter; zinc ion binding; positive regulation of transcription, DNA-dependent;
MYB	5	sequence-specific DNA binding transcription factor activity; DNA binding; regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
PTTG1	5	sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent;
RBPJ	5	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; negative regulation of transcription, DNA-dependent;
TADA2A	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription from RNA polymerase II promoter; zinc ion binding;
ZFP37	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; zinc ion binding;
ZNF169	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; zinc ion binding;
ZNF202	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; transcription from RNA polymerase II promoter; zinc ion binding;
ZNF215	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; zinc ion binding;
ZNF24	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; zinc ion binding; negative regulation of transcription, DNA-dependent;
ZNF287	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; zinc ion binding; positive regulation of transcription, DNA-dependent;
ZNF367	5	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; zinc ion binding;
ZNF396	5	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; zinc ion binding;
ZNF397	5	sequence-specific DNA binding transcription factor activity; DNA binding; cytoplasm; nucleus; zinc ion binding;
ZNF70	5	sequence-specific DNA binding transcription factor activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; zinc ion binding;
DEAF1	5	DNA binding; cytoplasm; nucleus; transcription from RNA polymerase II promoter; zinc ion binding;
GFI1B	5	DNA binding; nucleus; transcription from RNA polymerase II promoter; multicellular organismal development; zinc ion binding;
GRHL1	5	DNA binding; cytoplasm; nucleus; regulation of transcription, DNA-dependent; multicellular organismal development;
IGHMBP2	5	DNA binding; cytoplasm; nucleus; regulation of transcription, DNA-dependent; zinc ion binding;
IRF7	5	DNA binding; cytoplasm; nucleus; transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent;
MAPK1	5	DNA binding; cytoplasm; nucleus; Ras protein signal transduction; positive regulation of transcription, DNA-dependent;
SSRP1	5	DNA binding; cytoplasm; nucleus; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent;
ZFR	5	DNA binding; cytoplasm; nucleus; multicellular organismal development; zinc ion binding;
ZNF423	5	DNA binding; nucleus; zinc ion binding; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
ZNF521	5	DNA binding; nucleus; regulation of transcription, DNA-dependent; multicellular organismal development; zinc ion binding;
ZNF74	5	DNA binding; nucleus; regulation of transcription, DNA-dependent; multicellular organismal development; zinc ion binding;
ZNF77	5	DNA binding; cytoplasm; nucleus; regulation of transcription, DNA-dependent; zinc ion binding;
APBB1	5	cytoplasm; nucleus; regulation of transcription, DNA-dependent; nuclear speck; positive regulation of transcription, DNA-dependent;
ID2	5	cytoplasm; nucleus; multicellular organismal development; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
TFAP2A	5	cytoplasm; nucleus; transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with RREB1 (count: 0)

View in gBrowse

Region: chr6:7107830..7252213 View in gBrowse