ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	EBF1
Previous Symbol	EBF
Symbol Alias	OLF1
Approved Name	early B-cell factor 1
Previous Name	"early B-cell factor"
Location	5q34
Position	chr5:158122928-158526769, -1
External Links	HGNC: 3126 Entrez Gene: 1879 Ensembl: ENSG00000164330 UCSC: uc010jip.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
5q33.3	chr5:155700000-159900000	1 (1/0/0)

Gene related GO terms (count: 8)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0046872	metal ion binding	molecular function	IEA	200
GO:0045893	positive regulation of transcription, DNA-dependent	biological process	IEA	89
GO:0003677	DNA binding	molecular function	IEA	257
GO:0006351	transcription, DNA-dependent	biological process	IEA	281
GO:0003700	sequence-specific DNA binding transcription factor activity	molecular function	IEA	148
GO:0046983	protein dimerization activity	molecular function	IEA	28
GO:0007275	multicellular organismal development	biological process	IEA	79
GO:0005634	nucleus	cellular component	IEA	877

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with EBF1 (count: 12)

Gene Symbol	Pathway Count	Pathway List
TBX1	6	positive regulation of transcription, DNA-dependent; DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; protein dimerization activity; nucleus;
NPAS3	5	positive regulation of transcription, DNA-dependent; DNA binding; transcription, DNA-dependent; protein dimerization activity; nucleus;
ZNF287	5	positive regulation of transcription, DNA-dependent; DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus;
RREB1	5	positive regulation of transcription, DNA-dependent; DNA binding; sequence-specific DNA binding transcription factor activity; multicellular organismal development; nucleus;
HMGA1	5	positive regulation of transcription, DNA-dependent; DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus;
SOX8	5	positive regulation of transcription, DNA-dependent; DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus;
HINFP	5	positive regulation of transcription, DNA-dependent; DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus;
MYRF	5	positive regulation of transcription, DNA-dependent; DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus;
ETS1	5	positive regulation of transcription, DNA-dependent; DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus;
TFAP2B	5	positive regulation of transcription, DNA-dependent; DNA binding; sequence-specific DNA binding transcription factor activity; protein dimerization activity; nucleus;
SREBF1	5	DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; protein dimerization activity; nucleus;
HOXB1	5	DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; multicellular organismal development; nucleus;

Genes shared at least 2 KEGG pathways with EBF1 (count: 0)

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Region: chr5:158122928..158526769 View in gBrowse