ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TADA2A
Previous Symbol	TADA2L
Symbol Alias	ADA2, hADA2, ADA2A
Approved Name	transcriptional adaptor 2A
Previous Name	transcriptional adaptor 2 (ADA2 homolog, yeast)-like
Location	17q12-q21
Position	chr17:35766965-35838372, +
External Links	HGNC: 11531 Entrez Gene: 6871 Ensembl: ENSG00000108264
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 3)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_191	chr17:31889664-33323543 (NCBI Build 35 (hg17))	1774728	17q12	Deletion (hemizygous)	Paternal
CNV_Williams[2010]_7	chr17:31964475-33297438 (NCBI Build 36.1 (hg18))	1278621	17q12	Gain	Paternal
CNV_Williams[2010]_8	chr17:31979521-33318471 (NCBI Build 36.1 (hg18))	1276993	17q12	Loss

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	Cellular Component		2
GO:0005634	nucleus	Cellular Component	TAS[8552087]	770
GO:0004402	histone acetyltransferase activity	Molecular Function	IDA[9674425]	9
GO:0003712	transcription cofactor activity	Molecular Function	TAS[8552087]	17
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	TAS[8552087]	132
GO:0003682	chromatin binding	Molecular Function		48
GO:0003677	DNA binding	Molecular Function		220
GO:0001932	regulation of protein phosphorylation	Biological Process		4
GO:0072686	mitotic spindle	Cellular Component		2
GO:0043966	histone H3 acetylation	Biological Process	IDA[9674425]	6
GO:0031647	regulation of protein stability	Biological Process		4
GO:0031063	regulation of histone deacetylation	Biological Process		1
GO:0008270	zinc ion binding	Molecular Function		323
GO:0007067	mitosis	Biological Process		39
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	TAS[8552087]	62
GO:0005694	chromosome	Cellular Component		15
GO:0090043	regulation of tubulin deacetylation	Biological Process		1
GO:0000125	PCAF complex	Cellular Component	IDA[9674425]	2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TADA2A (count: 7)

Gene Symbol	Pathway Count	Pathway List
TAF10	6	nucleus; histone acetyltransferase activity; sequence-specific DNA binding transcription factor activity; histone H3 acetylation; transcription from RNA polymerase II promoter; PCAF complex;
GATA6	5	nucleus; sequence-specific DNA binding transcription factor activity; chromatin binding; zinc ion binding; transcription from RNA polymerase II promoter;
HINFP	5	nucleus; sequence-specific DNA binding transcription factor activity; chromatin binding; DNA binding; zinc ion binding;
NSD1	5	nucleus; transcription cofactor activity; chromatin binding; zinc ion binding; chromosome;
RREB1	5	nucleus; sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; transcription from RNA polymerase II promoter;
SSRP1	5	nucleus; chromatin binding; DNA binding; transcription from RNA polymerase II promoter; chromosome;
ZNF202	5	nucleus; sequence-specific DNA binding transcription factor activity; DNA binding; zinc ion binding; transcription from RNA polymerase II promoter;

Genes shared at least 2 KEGG pathways with TADA2A (count: 0)

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Region: chr17:35766965..35838372 View in gBrowse