ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DEAF1
Symbol Alias	NUDR, SPN, ZMYND5
Approved Name	DEAF1 transcription factor
Previous Name	"deformed epidermal autoregulatory factor 1 (Drosophila)"
Location	11p15.5
Position	chr11:644233-706715, -1
External Links	HGNC: 14677 Entrez Gene: 10522 Ensembl: ENSG00000177030 UCSC: uc001lqq.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by Literature SNP

Gene related studies (count: 0)

Gene related SNPs (count: 2)

Literature-origin SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs17758	chr11:644325(Fwd)	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant	1(0/1/0)
rs7124601	chr11:639273(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant	1(1/0/0)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0033599	regulation of mammary gland epithelial cell proliferation	biological process	IDA[18826651]	2
GO:0009653	anatomical structure morphogenesis	biological process	TAS[9773984]	28
GO:0003677	DNA binding	molecular function	IEA	257
GO:0006366	transcription from RNA polymerase II promoter	biological process	IEA	63
GO:0005634	nucleus	cellular component	IDA[19668219]	877
GO:0005667	transcription factor complex	cellular component	IEA	52
GO:0007281	germ cell development	biological process	TAS[9773984]	7
GO:0005515	protein binding	molecular function	IPI	1015
GO:0006357	regulation of transcription from RNA polymerase II promoter	biological process	IEA	46
GO:0048706	embryonic skeletal system development	biological process	ISS	4
GO:0008270	zinc ion binding	molecular function	IEA	367
GO:0005737	cytoplasm	cellular component	IDA[19668219]; IEA	781
GO:0005576	extracellular region	cellular component	IEA	267
GO:0001843	neural tube closure	biological process	ISS	12

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DEAF1 (count: 19)

Gene Symbol	Pathway Count	Pathway List
GFI1B	6	DNA binding; transcription from RNA polymerase II promoter; nucleus; transcription factor complex; protein binding; zinc ion binding;
FUS	5	DNA binding; nucleus; protein binding; zinc ion binding; cytoplasm;
RREB1	5	DNA binding; transcription from RNA polymerase II promoter; nucleus; zinc ion binding; cytoplasm;
ZFPM1	5	DNA binding; transcription factor complex; protein binding; zinc ion binding; cytoplasm;
KLF13	5	DNA binding; transcription from RNA polymerase II promoter; nucleus; protein binding; zinc ion binding;
TNFAIP3	5	DNA binding; nucleus; protein binding; zinc ion binding; cytoplasm;
IGHMBP2	5	DNA binding; nucleus; protein binding; zinc ion binding; cytoplasm;
ZFR	5	DNA binding; nucleus; protein binding; zinc ion binding; cytoplasm;
ZNF367	5	DNA binding; nucleus; regulation of transcription from RNA polymerase II promoter; zinc ion binding; cytoplasm;
PGR	5	DNA binding; nucleus; protein binding; zinc ion binding; cytoplasm;
RELA	5	DNA binding; nucleus; transcription factor complex; protein binding; cytoplasm;
ETS1	5	DNA binding; transcription from RNA polymerase II promoter; nucleus; transcription factor complex; protein binding;
SSRP1	5	DNA binding; transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm;
IRF7	5	DNA binding; transcription from RNA polymerase II promoter; nucleus; protein binding; cytoplasm;
GATA6	5	transcription from RNA polymerase II promoter; nucleus; transcription factor complex; protein binding; zinc ion binding;
SNCA	5	nucleus; protein binding; zinc ion binding; cytoplasm; extracellular region;
POU2F3	5	nucleus; transcription factor complex; protein binding; regulation of transcription from RNA polymerase II promoter; cytoplasm;
HOXA9	5	nucleus; transcription factor complex; protein binding; embryonic skeletal system development; cytoplasm;
CREBBP	5	nucleus; transcription factor complex; protein binding; zinc ion binding; cytoplasm;

Genes shared at least 2 KEGG pathways with DEAF1 (count: 0)

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Region: chr11:644233..706715 View in gBrowse