ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DEAF1
Symbol Alias	NUDR, SPN, ZMYND5
Approved Name	deformed epidermal autoregulatory factor 1 (Drosophila)
Location	11p15.5
Position	chr11:644225-706715, -
External Links	HGNC: 14677 Entrez Gene: 10522 Ensembl: ENSG00000177030 UCSC: uc001lqq.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by literature SNP

Gene related studies (count: 0)

Gene related SNPs (count: 2)

Literature-origin SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs7124601	Chr11:639273(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant	1(1/0/0)
rs17758	Chr11:644325(Fwd)	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	1(0/1/0)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005576	extracellular region	Cellular Component		240
GO:0005634	nucleus	Cellular Component	IDA[19668219]	770
GO:0005667	transcription factor complex	Cellular Component		51
GO:0005737	cytoplasm	Cellular Component	IDA[19668219]	690
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process		42
GO:0006366	transcription from RNA polymerase II promoter	Biological Process		62
GO:0007281	germ cell development	Biological Process	TAS[9773984]	7
GO:0008270	zinc ion binding	Molecular Function		323
GO:0009653	anatomical structure morphogenesis	Biological Process	TAS[9773984]	26
GO:0033599	regulation of mammary gland epithelial cell proliferation	Biological Process	IDA[18826651]	2
GO:0048706	embryonic skeletal system development	Biological Process		4
GO:0005515	protein binding	Molecular Function		910
GO:0003677	DNA binding	Molecular Function		220
GO:0001843	neural tube closure	Biological Process		10

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DEAF1 (count: 20)

Gene Symbol	Pathway Count	Pathway List
GFI1B	6	nucleus; transcription factor complex; transcription from RNA polymerase II promoter; zinc ion binding; protein binding; DNA binding;
SNCA	5	extracellular region; nucleus; cytoplasm; zinc ion binding; protein binding;
ETS1	5	nucleus; transcription factor complex; transcription from RNA polymerase II promoter; protein binding; DNA binding;
FUS	5	nucleus; cytoplasm; zinc ion binding; protein binding; DNA binding;
GATA6	5	nucleus; transcription factor complex; transcription from RNA polymerase II promoter; zinc ion binding; protein binding;
HOXA9	5	nucleus; transcription factor complex; cytoplasm; embryonic skeletal system development; protein binding;
IGHMBP2	5	nucleus; cytoplasm; zinc ion binding; protein binding; DNA binding;
IRF7	5	nucleus; cytoplasm; transcription from RNA polymerase II promoter; protein binding; DNA binding;
KLF13	5	nucleus; transcription from RNA polymerase II promoter; zinc ion binding; protein binding; DNA binding;
NCOR1	5	nucleus; transcription factor complex; cytoplasm; transcription from RNA polymerase II promoter; protein binding;
PGR	5	nucleus; cytoplasm; zinc ion binding; protein binding; DNA binding;
POU2F3	5	nucleus; transcription factor complex; cytoplasm; regulation of transcription from RNA polymerase II promoter; protein binding;
PRKCB	5	nucleus; cytoplasm; regulation of transcription from RNA polymerase II promoter; zinc ion binding; protein binding;
RELA	5	nucleus; transcription factor complex; cytoplasm; protein binding; DNA binding;
RREB1	5	nucleus; cytoplasm; transcription from RNA polymerase II promoter; zinc ion binding; DNA binding;
SSRP1	5	nucleus; cytoplasm; transcription from RNA polymerase II promoter; protein binding; DNA binding;
TNFAIP3	5	nucleus; cytoplasm; zinc ion binding; protein binding; DNA binding;
ZFR	5	nucleus; cytoplasm; zinc ion binding; protein binding; DNA binding;
ZNF367	5	nucleus; cytoplasm; regulation of transcription from RNA polymerase II promoter; zinc ion binding; DNA binding;
ZFPM1	5	transcription factor complex; cytoplasm; zinc ion binding; protein binding; DNA binding;

Genes shared at least 2 KEGG pathways with DEAF1 (count: 0)

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Region: chr11:644225..706715 View in gBrowse