ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	KLF13
Symbol Alias	RFLAT-1, BTEB3, NSLP1, FKLF-2
Approved Name	Kruppel-like factor 13
Location	15
Position	chr15:31619058-31670102, +
External Links	HGNC: 13672 Entrez Gene: 51621 Ensembl: ENSG00000169926 UCSC: uc001zfo.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_30	chr15:28797383-30302218 (NCBI36 / hg18)	1504836	15q13.2-15q13.3	dup

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
15q11.2-13.3	chr15:20700000-33600000	1 (1/0/0)
15q13.3	chr15:31200000-33600000	1 (1/0/0)

Gene related GO terms (count: 8)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005515	protein binding	Molecular Function	IPI[17513757]	910
GO:0005634	nucleus	Cellular Component		770
GO:0003677	DNA binding	Molecular Function		220
GO:0008285	negative regulation of cell proliferation	Biological Process		59
GO:0045647	negative regulation of erythrocyte differentiation	Biological Process		2
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	TAS[10023774]	62
GO:0008270	zinc ion binding	Molecular Function		323
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process		131

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with KLF13 (count: 11)

Gene Symbol	Pathway Count	Pathway List
ETS1	6	protein binding; nucleus; DNA binding; negative regulation of cell proliferation; transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
DEAF1	5	protein binding; nucleus; DNA binding; transcription from RNA polymerase II promoter; zinc ion binding;
ESRRA	5	protein binding; nucleus; DNA binding; zinc ion binding; positive regulation of transcription from RNA polymerase II promoter;
GATA6	5	protein binding; nucleus; transcription from RNA polymerase II promoter; zinc ion binding; positive regulation of transcription from RNA polymerase II promoter;
GFI1B	5	protein binding; nucleus; DNA binding; transcription from RNA polymerase II promoter; zinc ion binding;
HOXA5	5	protein binding; nucleus; DNA binding; negative regulation of erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter;
IRF7	5	protein binding; nucleus; DNA binding; transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
MLL	5	protein binding; nucleus; transcription from RNA polymerase II promoter; zinc ion binding; positive regulation of transcription from RNA polymerase II promoter;
NR5A1	5	protein binding; nucleus; DNA binding; zinc ion binding; positive regulation of transcription from RNA polymerase II promoter;
TFAP2A	5	protein binding; nucleus; negative regulation of cell proliferation; transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter;
ZBTB16	5	protein binding; nucleus; DNA binding; negative regulation of cell proliferation; zinc ion binding;

Genes shared at least 2 KEGG pathways with KLF13 (count: 0)

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Region: chr15:31619058..31670102 View in gBrowse