ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0008285
Name negative regulation of cell proliferation
Type biological process
No. of Genes in ADHDgene  65
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 65)

Literature-origin genes (count: 11)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
KANK2 KN motif and ankyrin repeat domains 2 19p13.2 1(0/1/0) IDA[17476305]
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 7q21 1(0/0/1) ISS
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0) IEA
PTPRJ protein tyrosine phosphatase, receptor type, J 11p11.2 1(0/1/0) IDA[14709717]
CDH13 cadherin 13 16q23.3 4(1/2/1) IDA[10737605]
ADRA1A adrenoceptor alpha 1A 8p21.2 3(2/1/0) TAS[10860850]
OPRM1 opioid receptor, mu 1 6q24-q25 1(1/0/0) TAS[2159143]
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) ISS
NPPC natriuretic peptide C 2q37.1 1(0/1/0) IEA
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) IDA
EREG epiregulin 4q21.21 1(0/0/1) ISS

Genes from other sources Help (count: 54)

Approved Symbol Approved Name Source Evidence[PMID]
ROR2 receptor tyrosine kinase-like orphan receptor 2 Mapped by significant region IMP[19486338]
FABP6 fatty acid binding protein 6, ileal Mapped by significant region TAS[9250612]
STK11 serine/threonine kinase 11 Mapped by CNV IMP[17216128]
MEN1 multiple endocrine neoplasia I Mapped by significant region IDA[15331604]
PBRM1 polybromo 1 Mapped by LD-proxy IMP
SSTR5 somatostatin receptor 5 Mapped by significant region TAS[9892014]
FOSL1 FOS-like antigen 1 Mapped by significant region IEA
FTH1 ferritin, heavy polypeptide 1 Mapped by significant region ISS
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) Mapped by significant region IMP[18818310]
FRK fyn-related kinase Mapped by significant region TAS[7664264]
TSC1 tuberous sclerosis 1 Mapped by PBA pathway IMP[10915759]
ZBTB16 zinc finger and BTB domain containing 16 Mapped by significant region IEA
GAS8 growth arrest-specific 8 Mapped by significant region TAS[9790751]
INPPL1 inositol polyphosphate phosphatase-like 1 Mapped by significant region IEA
TMEM127 transmembrane protein 127 Mapped by LD-proxy IMP
NDN necdin, melanoma antigen (MAGE) family member Mapped by CNV; Mapped by significant region TAS[9630521]
TSC2 tuberous sclerosis 2 Mapped by significant region IBA; ISS
KLF11 Kruppel-like factor 11 Mapped by significant region IDA
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 Mapped by significant region TAS[10438512]
NUP62 nucleoporin 62kDa Mapped by PBA pathway IDA[11013214]; ISS
CUL5 cullin 5 Mapped by significant region; Mapped by PBA pathway TAS[8681378]
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 Mapped by PBA pathway IDA[12671034]
NOX4 NADPH oxidase 4 Mapped by significant region ISS[10869423]
FKTN fukutin Mapped by significant region IMP[18808525]
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 Mapped by significant region IGI[9553041]
GJA1 gap junction protein, alpha 1, 43kDa Mapped by Literature SNP; Mapped by significant region IEA
TGFB1I1 transforming growth factor beta 1 induced transcript 1 Mapped by PBA pathway TAS[7929412]
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 Mapped by significant region TAS[9843971]
UMOD uromodulin Mapped by significant region TAS[2409603]
SKAP2 src kinase associated phosphoprotein 2 Mapped by significant region IEA
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mapped by CNV IEA
SPEG SPEG complex locus Mapped by significant region TAS[8663449]
NCK2 NCK adaptor protein 2 Mapped by PBA pathway TAS[9737977]
BTG4 B-cell translocation gene 4 Mapped by significant region TAS[10995567]
DEC1 deleted in esophageal cancer 1 Mapped by significant region TAS[10612805]
DFNA5 deafness, autosomal dominant 5 Mapped by CNV; Mapped by significant region IDA[18223688]
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IEA
KLF4 Kruppel-like factor 4 (gut) Mapped by significant region TAS[8702718]
HMGA1 high mobility group AT-hook 1 Mapped by PBA pathway IMP[16901784]
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 Mapped by significant region TAS[2187191]
FABP7 fatty acid binding protein 7, brain Mapped by significant region TAS[9250612]
PTPN14 protein tyrosine phosphatase, non-receptor type 14 Mapped by Literature SNP IMP
ADORA2A adenosine A2a receptor Mapped by CNV IEA
GPNMB glycoprotein (transmembrane) nmb Mapped by CNV; Mapped by significant region TAS[7814155]
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) Mapped by significant region TAS[9447982]
WNK2 WNK lysine deficient protein kinase 2 Mapped by significant region IMP[17667937]
PTPRK protein tyrosine phosphatase, receptor type, K Mapped by CNV; Mapped by significant region IDA[18276111]
TBRG1 transforming growth factor beta regulator 1 Mapped by significant region IMP[17110379]
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 Mapped by significant region IDA[11719219]
DIS3L2 DIS3 mitotic control homolog (S. cerevisiae)-like 2 Mapped by LD-proxy IMP
KLF13 Kruppel-like factor 13 Mapped by CNV; Mapped by significant region IEA
APC adenomatous polyposis coli Mapped by LD-proxy; Mapped by PBA pathway IDA[8521819]
NF2 neurofibromin 2 (merlin) Mapped by PBA pathway IDA[12444102]; IMP[17210637]
CDK10 cyclin-dependent kinase 10 Mapped by significant region TAS[8208557]