ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	ZFPM1
Symbol Alias	FOG1, FOG, ZNF89A
Approved Name	zinc finger protein, multitype 1
Location	16q24.3
Position	chr16:88519725-88601574, +
External Links	HGNC: 19762 Entrez Gene: 161882 Ensembl: ENSG00000179588 UCSC: uc002fkv.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 36)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 36)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003181	atrioventricular valve morphogenesis	Biological Process		1
GO:0003151	outflow tract morphogenesis	Biological Process		12
GO:0003195	tricuspid valve formation	Biological Process		2
GO:0003192	mitral valve formation	Biological Process		1
GO:0001085	RNA polymerase II transcription factor binding	Molecular Function	IPI[15920471]	10
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular Function	IDA[15920471]	7
GO:0002295	T-helper cell lineage commitment	Biological Process		1
GO:0001102	RNA polymerase II activating transcription factor binding	Molecular Function		6
GO:0007596	blood coagulation	Biological Process		83
GO:0005737	cytoplasm	Cellular Component		690
GO:0008270	zinc ion binding	Molecular Function		323
GO:0008134	transcription factor binding	Molecular Function	IPI[12483298]	38
GO:0005515	protein binding	Molecular Function		910
GO:0003677	DNA binding	Molecular Function		220
GO:0005667	transcription factor complex	Cellular Component	IDA[15920471]	51
GO:0005654	nucleoplasm	Cellular Component		183
GO:0071733	transcriptional activation by promoter-enhancer looping	Biological Process		1
GO:0060413	atrial septum morphogenesis	Biological Process		4
GO:0060412	ventricular septum morphogenesis	Biological Process		5
GO:0060377	negative regulation of mast cell differentiation	Biological Process		1
GO:0032091	negative regulation of protein binding	Biological Process		4
GO:0032642	regulation of chemokine production	Biological Process		1
GO:0030220	platelet formation	Biological Process	IGI[11675338]	1
GO:0030851	granulocyte differentiation	Biological Process		4
GO:0030218	erythrocyte differentiation	Biological Process		4
GO:0030219	megakaryocyte differentiation	Biological Process		1
GO:0010724	regulation of definitive erythrocyte differentiation	Biological Process	IDA[15920471]; IMP[17207461]	1
GO:0017053	transcriptional repressor complex	Cellular Component	IDA[15920471]	8
GO:0060318	definitive erythrocyte differentiation	Biological Process		2
GO:0060319	primitive erythrocyte differentiation	Biological Process		2
GO:0045599	negative regulation of fat cell differentiation	Biological Process		5
GO:0055008	cardiac muscle tissue morphogenesis	Biological Process		2
GO:0045078	positive regulation of interferon-gamma biosynthetic process	Biological Process		2
GO:0045403	negative regulation of interleukin-4 biosynthetic process	Biological Process		1
GO:0035162	embryonic hemopoiesis	Biological Process		4
GO:0035855	megakaryocyte development	Biological Process		2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ZFPM1 (count: 20)

Gene Symbol	Pathway Count	Pathway List
HEY2	9	outflow tract morphogenesis; tricuspid valve formation; RNA polymerase II activating transcription factor binding; cytoplasm; transcription factor binding; protein binding; atrial septum morphogenesis; ventricular septum morphogenesis; transcriptional repressor complex;
KDM1A	8	RNA polymerase II transcription factor binding; blood coagulation; transcription factor binding; protein binding; transcription factor complex; nucleoplasm; negative regulation of protein binding; granulocyte differentiation;
HES1	7	outflow tract morphogenesis; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; cytoplasm; transcription factor binding; protein binding; DNA binding; ventricular septum morphogenesis;
NCOR1	7	RNA polymerase II activating transcription factor binding; cytoplasm; protein binding; transcription factor complex; nucleoplasm; transcriptional repressor complex; definitive erythrocyte differentiation;
GATA6	6	blood coagulation; zinc ion binding; transcription factor binding; protein binding; transcription factor complex; nucleoplasm;
MAPK1	6	blood coagulation; cytoplasm; transcription factor binding; protein binding; DNA binding; nucleoplasm;
E2F5	6	cytoplasm; transcription factor binding; protein binding; DNA binding; transcription factor complex; nucleoplasm;
RELA	6	cytoplasm; transcription factor binding; protein binding; DNA binding; transcription factor complex; nucleoplasm;
ISL1	5	outflow tract morphogenesis; RNA polymerase II activating transcription factor binding; cytoplasm; zinc ion binding; atrial septum morphogenesis;
RBPJ	5	outflow tract morphogenesis; cytoplasm; protein binding; DNA binding; nucleoplasm;
VEGFA	5	outflow tract morphogenesis; blood coagulation; cytoplasm; protein binding; primitive erythrocyte differentiation;
DHX9	5	RNA polymerase II transcription factor binding; cytoplasm; protein binding; DNA binding; nucleoplasm;
GFI1B	5	RNA polymerase II transcription factor binding; zinc ion binding; protein binding; DNA binding; transcription factor complex;
DEAF1	5	cytoplasm; zinc ion binding; protein binding; DNA binding; transcription factor complex;
FOXP2	5	cytoplasm; zinc ion binding; transcription factor binding; DNA binding; transcription factor complex;
FUS	5	cytoplasm; zinc ion binding; protein binding; DNA binding; nucleoplasm;
IGHMBP2	5	cytoplasm; zinc ion binding; transcription factor binding; protein binding; DNA binding;
PGR	5	cytoplasm; zinc ion binding; protein binding; DNA binding; nucleoplasm;
HMGA1	5	transcription factor binding; protein binding; DNA binding; transcription factor complex; nucleoplasm;
MED1	5	transcription factor binding; protein binding; nucleoplasm; embryonic hemopoiesis; megakaryocyte development;

Genes shared at least 2 KEGG pathways with ZFPM1 (count: 0)

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Region: chr16:88519725..88601574 View in gBrowse