ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0008134
Name	transcription factor binding
Type	molecular function
No. of Genes in ADHDgene	44
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 44)

Literature-origin genes (count: 8)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
LMO4	LIM domain only 4	1p22.3	1(0/1/0)	ISS
FOXP2	forkhead box P2	7q31	1(1/0/0)	IBA
FOXP1	forkhead box P1	3p14.1	1(0/0/1)	IBA
ARRB1	arrestin, beta 1	11q13	2(1/1/0)	IPI[16325578]
HES1	hes family bHLH transcription factor 1	3q28-q29	1(1/0/0)	NAS[17611704]
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	9q21.32	1(1/0/0)	IDA[9751710]; IPI[8687460]
HES6	hes family bHLH transcription factor 6	2q37.3	1(0/1/0)	NAS[17611704]
MEIS2	Meis homeobox 2	15q14	1(0/0/1)	ISS

Genes from other sources (count: 36)

Approved Symbol	Approved Name	Source	Evidence[PMID]
FOXD4	forkhead box D4	Mapped by CNV	IBA
ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	Mapped by significant region	NAS[10698492]
DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3	Mapped by significant region	IPI
HOXA7	homeobox A7	Mapped by significant region	IPI[18973687]
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	Mapped by PBA pathway	IPI[14701856]
UBE2I	ubiquitin-conjugating enzyme E2I	Mapped by significant region	IPI[19744555]
SOX8	SRY (sex determining region Y)-box 8	Mapped by significant region	IEA
KDM1A	lysine (K)-specific demethylase 1A	Mapped by LD-proxy	IDA
STK36	serine/threonine kinase 36	Mapped by significant region	IDA[10806483]
FOXE1	forkhead box E1 (thyroid transcription factor 2)	Mapped by significant region	IBA
FOXL1	forkhead box L1	Mapped by significant region	IBA
MAPK9	mitogen-activated protein kinase 9	Mapped by CNV	IDA[10376527]
FOXR1	forkhead box R1	Mapped by significant region	IBA
SORBS3	sorbin and SH3 domain containing 3	Mapped by PBA pathway	IEA
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	Mapped by PBA pathway	ISS
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	Mapped by CNV	ISS
NAAA	N-acylethanolamine acid amidase	Mapped by CNV	IPI
HEY2	hes-related family bHLH transcription factor with YRPW motif 2	Mapped by significant region	NAS[17611704]
CREBBP	CREB binding protein	Mapped by significant region	IPI[15509593]
DAXX	death-domain associated protein	Mapped by PBA pathway	IDA[10698492]
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy	IEA
KCTD1	potassium channel tetramerization domain containing 1	Mapped by significant region	IPI[19115315]
HMGA1	high mobility group AT-hook 1	Mapped by PBA pathway	IDA[10428834]
FOXG1	forkhead box G1	Mapped by significant region	IBA
DRAP1	DR1-associated protein 1 (negative cofactor 2 alpha)	Mapped by significant region	IEA
ZFPM1	zinc finger protein, FOG family member 1	Mapped by significant region	IPI[12483298]
RELA	v-rel avian reticuloendotheliosis viral oncogene homolog A	Mapped by significant region	IPI[10849440]
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	Mapped by significant region	IBA
FOXF1	forkhead box F1	Mapped by significant region	IBA
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	Mapped by significant region	IPI[16964248]
IGHMBP2	immunoglobulin mu binding protein 2	Mapped by CNV; Mapped by significant region	IPI[19299493]
AIP	aryl hydrocarbon receptor interacting protein	Mapped by significant region	TAS[9447995]
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway	IPI[17641689]
RNF19A	ring finger protein 19A, RBR E3 ubiquitin protein ligase	Mapped by PBA pathway	TAS[10976766]
KAT8	K(lysine) acetyltransferase 8	Mapped by CNV	IDA[11742995]
GATA6	GATA binding protein 6	Mapped by significant region	IPI[15016828]