ADHDgene Database

Gene Report

Basic Info

Approved Symbol	LMO4
Approved Name	LIM domain only 4
Location	1p22.3
Position	chr1:87794151-87814606, +
External Links	HGNC: 6644 Entrez Gene: 8543 Ensembl: ENSG00000143013 UCSC: uc001dmi.2
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Ribases M, 2009(a)	No available data. No significant association with ADHD was found.	Non-significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 16)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0021514	ventral spinal cord interneuron differentiation	Biological Process		1
GO:0008270	zinc ion binding	Molecular Function		323
GO:0008134	transcription factor binding	Molecular Function		38
GO:0006366	transcription from RNA polymerase II promoter	Biological Process		62
GO:0042659	regulation of cell fate specification	Biological Process		1
GO:0031333	negative regulation of protein complex assembly	Biological Process		2
GO:0021527	spinal cord association neuron differentiation	Biological Process		2
GO:0021522	spinal cord motor neuron differentiation	Biological Process		3
GO:0001158	enhancer sequence-specific DNA binding	Molecular Function		2
GO:0005667	transcription factor complex	Cellular Component		51
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	TAS[10209267]	132
GO:0003281	ventricular septum development	Biological Process		5
GO:0001843	neural tube closure	Biological Process		10
GO:0050865	regulation of cell activation	Biological Process		1
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process		131
GO:0048538	thymus development	Biological Process		14

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with LMO4 (count: 6)

Gene Symbol	Pathway Count	Pathway List
GATA6	6	zinc ion binding; transcription factor binding; transcription from RNA polymerase II promoter; transcription factor complex; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
ISL1	5	zinc ion binding; spinal cord motor neuron differentiation; enhancer sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
KLF4	5	zinc ion binding; transcription from RNA polymerase II promoter; transcription factor complex; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
ETS1	5	transcription factor binding; transcription from RNA polymerase II promoter; transcription factor complex; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter;
FOXE1	5	transcription factor binding; transcription factor complex; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; thymus development;
HES1	5	transcription factor binding; sequence-specific DNA binding transcription factor activity; ventricular septum development; positive regulation of transcription from RNA polymerase II promoter; thymus development;

Genes shared at least 2 KEGG pathways with LMO4 (count: 0)

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Region: chr1:87794151..87814606 View in gBrowse