ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007596
Name blood coagulation
Type biological process
No. of Genes in ADHDgene  85
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 85)

Literature-origin genes (count: 13)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ARRB2 arrestin, beta 2 17p13 1(1/0/0) TAS
ADRA2B adrenoceptor alpha 2B 2q11.1 1(1/0/0) TAS
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) TAS
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 19q13.11 1(1/0/0) TAS
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 1(1/0/0) TAS
ADRA2A adrenoceptor alpha 2A 10q25.2 13(4/9/0) TAS
ARRB1 arrestin, beta 1 11q13 2(1/1/0) TAS
ADRA2C adrenoceptor alpha 2C 4p16.3 7(2/4/1) TAS
PRKG1 protein kinase, cGMP-dependent, type I 10q11.2 2(0/1/1) TAS
DGKH diacylglycerol kinase, eta 13q13.3 2(1/1/0) TAS
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 Xq28 1(0/1/0) TAS
PTPRJ protein tyrosine phosphatase, receptor type, J 11p11.2 1(0/1/0) IEA
SH2B1 SH2B adaptor protein 1 16p11.2 1(0/1/0) TAS

Genes from other sources Help (count: 72)

Approved Symbol Approved Name Source Evidence[PMID]
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 Mapped by significant region TAS
STX4 syntaxin 4 Mapped by CNV TAS
SH2B3 SH2B adaptor protein 3 Mapped by LD-proxy TAS
PDE2A phosphodiesterase 2A, cGMP-stimulated Mapped by significant region TAS
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region TAS
SPN sialophorin Mapped by CNV TAS
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) Mapped by significant region TAS
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 Mapped by significant region IEA
TRPC3 transient receptor potential cation channel, subfamily C, member 3 Mapped by PBA pathway TAS
KIF11 kinesin family member 11 Mapped by PBA pathway TAS
APOA1 apolipoprotein A-I Mapped by significant region TAS
DOCK8 dedicator of cytokinesis 8 Mapped by CNV TAS
YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 Mapped by CNV TAS
TUBA4A tubulin, alpha 4a Mapped by significant region TAS
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Mapped by significant region TAS
GATA6 GATA binding protein 6 Mapped by significant region TAS
ZFPM1 zinc finger protein, FOG family member 1 Mapped by significant region TAS
KIF22 kinesin family member 22 Mapped by CNV TAS
AMICA1 adhesion molecule, interacts with CXADR antigen 1 Mapped by significant region TAS
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region TAS
PRCP prolylcarboxypeptidase (angiotensinase C) Mapped by significant region TAS
HBG2 hemoglobin, gamma G Mapped by CNV TAS
RAB27A RAB27A, member RAS oncogene family Mapped by LD-proxy IEA
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 Mapped by significant region TAS
ALDOA aldolase A, fructose-bisphosphate Mapped by CNV TAS
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy TAS
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) Mapped by LD-proxy TAS
F2RL2 coagulation factor II (thrombin) receptor-like 2 Mapped by PBA pathway TAS
JMJD1C jumonji domain containing 1C Mapped by PBA pathway TAS
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV TAS
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) Mapped by CNV TAS
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) Mapped by significant region TAS
DAGLA diacylglycerol lipase, alpha Mapped by significant region TAS
FN1 fibronectin 1 Mapped by significant region TAS
MMP1 matrix metallopeptidase 1 (interstitial collagenase) Mapped by significant region TAS
KIF23 kinesin family member 23 Mapped by PBA pathway TAS
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region TAS
EHD1 EH-domain containing 1 Mapped by significant region TAS
ADORA2A adenosine A2a receptor Mapped by CNV TAS[10899090]
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 Mapped by significant region TAS
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 Mapped by significant region TAS
KLC2 kinesin light chain 2 Mapped by significant region TAS
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 Mapped by CNV IEA
ORAI1 ORAI calcium release-activated calcium modulator 1 Mapped by PBA pathway TAS
ESAM endothelial cell adhesion molecule Mapped by significant region TAS
KIF2C kinesin family member 2C Mapped by PBA pathway TAS
F7 coagulation factor VII (serum prothrombin conversion accelerator) Mapped by CNV TAS
HABP4 hyaluronan binding protein 4 Mapped by significant region TAS
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Mapped by CNV TAS
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 Mapped by significant region TAS
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Mapped by CNV TAS
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Mapped by CNV TAS
DGKG diacylglycerol kinase, gamma 90kDa Mapped by Literature SNP TAS
MYB v-myb avian myeloblastosis viral oncogene homolog Mapped by significant region TAS
F10 coagulation factor X Mapped by CNV IC[17469850]; TAS
POTEKP POTE ankyrin domain family, member K, pseudogene Mapped by significant region TAS
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 Mapped by Literature SNP TAS
CABLES1 Cdk5 and Abl enzyme substrate 1 Mapped by significant region TAS
SYK spleen tyrosine kinase Mapped by significant region TAS
TRPC6 transient receptor potential cation channel, subfamily C, member 6 Mapped by significant region TAS
LMAN1 lectin, mannose-binding, 1 Mapped by LD-proxy; Mapped by significant region; Mapped by PBA pathway TAS[9546392]
GP1BB glycoprotein Ib (platelet), beta polypeptide Mapped by CNV TAS
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Mapped by Literature SNP TAS
JAM3 junctional adhesion molecule 3 Mapped by significant region TAS
AKAP10 A kinase (PRKA) anchor protein 10 Mapped by significant region TAS
VEGFB vascular endothelial growth factor B Mapped by significant region TAS
KIFC1 kinesin family member C1 Mapped by LD-proxy TAS
MGLL monoglyceride lipase Mapped by PBA pathway TAS
CFL1 cofilin 1 (non-muscle) Mapped by significant region TAS
KDM1A lysine (K)-specific demethylase 1A Mapped by LD-proxy TAS
STXBP3 syntaxin binding protein 3 Mapped by CNV TAS
EHD3 EH-domain containing 3 Mapped by CNV TAS