ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CTNND2
Symbol Alias	NPRAP, GT24
Approved Name	catenin (cadherin-associated protein), delta 2
Previous Name	"catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)"
Name Alias	"neural plakophilin-related arm-repeat protein"
Location	5p15.2
Position	chr5:10971952-11904155, -1
External Links	HGNC: 2516 Entrez Gene: 1501 Ensembl: ENSG00000169862 UCSC: uc003jfa.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_57	chr5:11540585-11571704 (NCBI Build 35 (hg17))	31120	5p15.2	Deletion (hemizygous)	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
5p	chr5:0-48400000	1 (1/0/0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043204	perikaryon	cellular component	IEA	12
GO:0006351	transcription, DNA-dependent	biological process	IEA	281
GO:0007165	signal transduction	biological process	TAS[9223106]	189
GO:0007158	neuron cell-cell adhesion	biological process	NAS	5
GO:0005634	nucleus	cellular component	IEA	877
GO:0006355	regulation of transcription, DNA-dependent	biological process	IEA	182
GO:0005515	protein binding	molecular function	IPI[19706687]	1015
GO:0007612	learning	biological process	IEA	13
GO:0048167	regulation of synaptic plasticity	biological process	IEA	9
GO:0007155	cell adhesion	biological process	TAS[9223106]	99
GO:0005912	adherens junction	cellular component	IEA	9
GO:0007275	multicellular organismal development	biological process	IEA	79
GO:0001763	morphogenesis of a branching structure	biological process	IEA	3
GO:0005737	cytoplasm	cellular component	TAS[9342840]	781

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CTNND2 (count: 24)

Gene Symbol	Pathway Count	Pathway List
LPXN	7	transcription, DNA-dependent; signal transduction; nucleus; regulation of transcription, DNA-dependent; protein binding; cell adhesion; cytoplasm;
MAPK1	6	perikaryon; transcription, DNA-dependent; signal transduction; nucleus; protein binding; cytoplasm;
FLII	6	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; multicellular organismal development; cytoplasm;
CTNND1	6	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; cell adhesion; cytoplasm;
APBB1	6	transcription, DNA-dependent; signal transduction; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
TH	5	perikaryon; nucleus; protein binding; learning; cytoplasm;
PSPC1	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
LMX1B	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; multicellular organismal development;
SCAI	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
EEF1D	5	transcription, DNA-dependent; signal transduction; nucleus; regulation of transcription, DNA-dependent; protein binding;
IGHMBP2	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
TERF2IP	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
GRHL1	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; multicellular organismal development; cytoplasm;
HOXB1	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; multicellular organismal development; cytoplasm;
PNN	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; cell adhesion; cytoplasm;
PTPN14	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
DAXX	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
HABP4	5	transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
NR4A2	5	transcription, DNA-dependent; signal transduction; nucleus; protein binding; cytoplasm;
HOXA9	5	transcription, DNA-dependent; nucleus; protein binding; multicellular organismal development; cytoplasm;
PRKAA1	5	transcription, DNA-dependent; signal transduction; nucleus; regulation of transcription, DNA-dependent; protein binding;
TNR	5	signal transduction; neuron cell-cell adhesion; nucleus; cell adhesion; cytoplasm;
CREBBP	5	signal transduction; nucleus; regulation of transcription, DNA-dependent; protein binding; cytoplasm;
ARVCF	5	nucleus; protein binding; cell adhesion; multicellular organismal development; cytoplasm;

Genes shared at least 2 KEGG pathways with CTNND2 (count: 0)

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Region: chr5:10971952..11904155 View in gBrowse