ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PLEKHH2
Symbol Alias	KIAA2028, PLEKHH1L
Approved Name	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Location	2p22
Position	chr2:43864412-43995126, +
External Links	HGNC: 30506 Entrez Gene: 130271 Ensembl: ENSG00000152527 UCSC: uc010yny.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_9	chr2:43688504-43796506 (NCBI Build 35 (hg17))	108003	2p21	Deletion (hemizygous)	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 8)

ID	Name	Type	No. of Genes in ADHDgene
GO:0030864	cortical actin cytoskeleton	Cellular Component	5
GO:0030027	lamellipodium	Cellular Component	27
GO:0030835	negative regulation of actin filament depolymerization	Biological Process	2
GO:0003779	actin binding	Molecular Function	46
GO:0005886	plasma membrane	Cellular Component	772
GO:0016021	integral to membrane	Cellular Component	845
GO:0005543	phospholipid binding	Molecular Function	61
GO:0005737	cytoplasm	Cellular Component	690

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PLEKHH2 (count: 0)

Genes shared at least 2 KEGG pathways with PLEKHH2 (count: 0)

View in gBrowse

Region: chr2:43864412..43995126 View in gBrowse