ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04120
Name Ubiquitin mediated proteolysis
No. of Genes in ADHDgene  34
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 34)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
TRIM32 tripartite motif containing 32 9q33.1 1(0/0/1)
FANCL Fanconi anemia, complementation group L 2p16.1 1(0/1/0)
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8q13.3 1(0/0/1)
PARK2 parkin RBR E3 ubiquitin protein ligase 6q25.2-q27 1(1/0/0)

Genes from other sources Help(count: 30)

Approved Symbol Approved Name Location Source
ANAPC4 anaphase promoting complex subunit 4 4p15.31 Mapped by CNV
UBE4A ubiquitination factor E4A 11q23.3 Mapped by significant region
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 16p13 Mapped by significant region
UBE2H ubiquitin-conjugating enzyme E2H 7q32 Mapped by LD-proxy
UBE2I ubiquitin-conjugating enzyme E2I 16p13.3 Mapped by significant region
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 11q23.3 Mapped by significant region
SOCS1 suppressor of cytokine signaling 1 16p13.13 Mapped by significant region
CDC26 cell division cycle 26 9q32 Mapped by significant region
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 15q13 Mapped by significant region
FBXO4 F-box protein 4 5p12 Mapped by significant region
BIRC6 baculoviral IAP repeat containing 6 2p22.3 Mapped by CNV
UBE2L6 ubiquitin-conjugating enzyme E2L 6 11q12.1 Mapped by significant region
BIRC2 baculoviral IAP repeat containing 2 11q22 Mapped by significant region
SYVN1 synovial apoptosis inhibitor 1, synoviolin 11q13 Mapped by significant region
CUL5 cullin 5 11q22.3 Mapped by significant region; Mapped by PBA pathway
PRPF19 pre-mRNA processing factor 19 11q12.2 Mapped by significant region
UBOX5 U-box domain containing 5 20p13 Mapped by CNV
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 16p12.3 Mapped by significant region
BIRC3 baculoviral IAP repeat containing 3 11q22 Mapped by significant region
ERCC8 excision repair cross-complementing rodent repair deficiency, complementation group 8 5q12.1 Mapped by CNV
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 18q21 Mapped by significant region
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 16p13.3 Mapped by significant region
TRIP12 thyroid hormone receptor interactor 12 2q36.3 Mapped by PBA pathway
UBA6 ubiquitin-like modifier activating enzyme 6 4q13.2 Mapped by significant region
MID1 midline 1 (Opitz/BBB syndrome) Xp22 Mapped by PBA pathway
DDB1 damage-specific DNA binding protein 1, 127kDa 11q12-q13 Mapped by significant region
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 4q21 Mapped by CNV
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 5p13 Mapped by significant region
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 4q21.1-q21.3 Mapped by CNV
UBE3A ubiquitin protein ligase E3A 15q11.2 Mapped by CNV; Mapped by significant region