ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SOD3
Symbol Alias	EC-SOD
Approved Name	superoxide dismutase 3, extracellular
Location	4pter-q21
Position	chr4:24797085-24802467, +
External Links	HGNC: 11181 Entrez Gene: 6649 Ensembl: ENSG00000109610 UCSC: uc003gqz.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_18	chr4:23596065-27014659 (NCBI Build 36.1 (hg18))	3365040	4p15.2	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0031012	extracellular matrix	Cellular Component		28
GO:0019430	removal of superoxide radicals	Biological Process		4
GO:0008270	zinc ion binding	Molecular Function		323
GO:0008201	heparin binding	Molecular Function		26
GO:0046688	response to copper ion	Biological Process		1
GO:0005615	extracellular space	Cellular Component		126
GO:0005515	protein binding	Molecular Function	IPI[15528465]	910
GO:0005507	copper ion binding	Molecular Function		9
GO:0004784	superoxide dismutase activity	Molecular Function		2
GO:0001666	response to hypoxia	Biological Process		34
GO:0005829	cytosol	Cellular Component		447
GO:0005802	trans-Golgi network	Cellular Component		28
GO:0005739	mitochondrion	Cellular Component		183
GO:0005634	nucleus	Cellular Component		770

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SOD3 (count: 5)

Gene Symbol	Pathway Count	Pathway List
CCS	7	removal of superoxide radicals; zinc ion binding; protein binding; copper ion binding; superoxide dismutase activity; cytosol; nucleus;
SNCA	6	zinc ion binding; protein binding; copper ion binding; cytosol; mitochondrion; nucleus;
PARK2	5	zinc ion binding; protein binding; cytosol; mitochondrion; nucleus;
CRYAB	5	protein binding; response to hypoxia; cytosol; mitochondrion; nucleus;
TH	5	protein binding; response to hypoxia; cytosol; mitochondrion; nucleus;

Genes shared at least 2 KEGG pathways with SOD3 (count: 0)

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Region: chr4:24797085..24802467 View in gBrowse