ADHDgene Database

Gene Report

Basic Info

Approved Symbol	G2E3
Previous Symbol	KIAA1333
Symbol Alias	FLJ20333, PHF7B
Approved Name	G2/M-phase specific E3 ubiquitin protein ligase
Previous Name	KIAA1333
Name Alias	PHD finger protein 7B
Location	14q12
Position	chr14:31028329-31089269, +
External Links	HGNC: 20338 Entrez Gene: 55632 Ensembl: ENSG00000092140 UCSC: uc001wqk.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
14q12	chr14:24600000-33300000	1 (1/0/0)

Gene related GO terms (count: 10)

ID	Name	Type	No. of Genes in ADHDgene
GO:0043066	negative regulation of apoptotic process	Biological Process	77
GO:0043231	intracellular membrane-bounded organelle	Cellular Component	62
GO:0006915	apoptotic process	Biological Process	111
GO:0008270	zinc ion binding	Molecular Function	323
GO:0005737	cytoplasm	Cellular Component	690
GO:0005794	Golgi apparatus	Cellular Component	157
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	52
GO:0005730	nucleolus	Cellular Component	243
GO:0000209	protein polyubiquitination	Biological Process	23
GO:0001824	blastocyst development	Biological Process	3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with G2E3 (count: 8)

Gene Symbol	Pathway Count	Pathway List
AATF	5	negative regulation of apoptotic process; apoptotic process; cytoplasm; Golgi apparatus; nucleolus;
BIRC2	5	negative regulation of apoptotic process; apoptotic process; zinc ion binding; ubiquitin-protein ligase activity; protein polyubiquitination;
BIRC3	5	negative regulation of apoptotic process; apoptotic process; zinc ion binding; cytoplasm; ubiquitin-protein ligase activity;
KLHL20	5	negative regulation of apoptotic process; cytoplasm; Golgi apparatus; ubiquitin-protein ligase activity; nucleolus;
TFAP2A	5	negative regulation of apoptotic process; intracellular membrane-bounded organelle; cytoplasm; Golgi apparatus; nucleolus;
TRIM32	5	negative regulation of apoptotic process; zinc ion binding; cytoplasm; ubiquitin-protein ligase activity; protein polyubiquitination;
PARK2	5	zinc ion binding; cytoplasm; Golgi apparatus; ubiquitin-protein ligase activity; protein polyubiquitination;
TRIM5	5	zinc ion binding; cytoplasm; Golgi apparatus; ubiquitin-protein ligase activity; nucleolus;

Genes shared at least 2 KEGG pathways with G2E3 (count: 0)

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Region: chr14:31028329..31089269 View in gBrowse