ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0043231
Name intracellular membrane-bounded organelle
Type cellular component
No. of Genes in ADHDgene  65
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 65)

Literature-origin genes (count: 14)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ATXN1 ataxin 1 6p23 1(0/0/1) IDA
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 2q37 1(0/0/1) NAS
CLOCK clock circadian regulator 4q12 2(2/0/0) IDA
COMT catechol-O-methyltransferase 22q11.21 29(7/22/0) IDA
GPRC5B G protein-coupled receptor, class C, group 5, member B 16p12 1(1/0/0) IDA
FHIT fragile histidine triad 3p14.2 1(0/0/1) IDA
MOBP myelin-associated oligodendrocyte basic protein 3p21.33 1(0/0/1) IDA
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 12q23 2(2/0/0) IDA
RBMS3 RNA binding motif, single stranded interacting protein 3 3p24-p23 1(0/1/0) IDA
STS steroid sulfatase (microsomal), isozyme S Xp22.32 3(2/1/0) TAS[6957717]
CNTF ciliary neurotrophic factor 11q12 1(1/0/0) IDA
FADS1 fatty acid desaturase 1 11q12-q13.1 3(1/2/0) NAS[10601301]
SEC16B SEC16 homolog B (S. cerevisiae) 1q25.2 1(0/1/0) IDA
SYT2 synaptotagmin II 1q32.1 1(1/0/0) IDA

Genes from other sources Help (count: 51)

Approved Symbol Approved Name Source Evidence[PMID]
CLCC1 chloride channel CLIC-like 1 Mapped by CNV IDA
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 Mapped by LD-proxy NAS
ZFP91 ZFP91 zinc finger protein Mapped by significant region IDA
FMO5 flavin containing monooxygenase 5 Mapped by CNV NAS
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 Mapped by LD-proxy NAS
PATL1 protein associated with topoisomerase II homolog 1 (yeast) Mapped by significant region IDA
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 Mapped by significant region IDA
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 Mapped by significant region IDA[9133646]
TSC1 tuberous sclerosis 1 Mapped by PBA pathway IEA
PGR progesterone receptor Mapped by significant region IDA
MAML1 mastermind-like 1 (Drosophila) Mapped by CNV IDA
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) Mapped by significant region IDA[12872255]
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) Mapped by significant region IDA
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) Mapped by significant region IDA
TRIM22 tripartite motif containing 22 Mapped by CNV IDA
CTGF connective tissue growth factor Mapped by significant region IDA
G2E3 G2/M-phase specific E3 ubiquitin protein ligase Mapped by significant region IDA
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) Mapped by significant region ISS
MIB1 mindbomb E3 ubiquitin protein ligase 1 Mapped by significant region IDA
SLU7 SLU7 splicing factor homolog (S. cerevisiae) Mapped by significant region; Mapped by PBA pathway IDA
FXYD2 FXYD domain containing ion transport regulator 2 Mapped by significant region IEA
PARM1 prostate androgen-regulated mucin-like protein 1 Mapped by CNV IDA
PRDX5 peroxiredoxin 5 Mapped by significant region IDA[15785239]
NUP62 nucleoporin 62kDa Mapped by PBA pathway IDA
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) Mapped by significant region IDA
LTC4S leukotriene C4 synthase Mapped by CNV TAS[1454853]
RAB11FIP3 RAB11 family interacting protein 3 (class II) Mapped by significant region IDA
AMBP alpha-1-microglobulin/bikunin precursor Mapped by significant region IEA
BYSL bystin-like Mapped by CNV IDA
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase Mapped by significant region IDA
RABEPK Rab9 effector protein with kelch motifs Mapped by significant region IDA
MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) Mapped by significant region IDA
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 Mapped by significant region NAS
PTCH1 patched 1 Mapped by significant region IDA[11278759]
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 Mapped by Literature SNP IDA
PICALM phosphatidylinositol binding clathrin assembly protein Mapped by significant region IDA
SQLE squalene epoxidase Mapped by CNV NAS
STAP1 signal transducing adaptor family member 1 Mapped by significant region IDA
STX16 syntaxin 16 Mapped by PBA pathway IDA
PLCH1 phospholipase C, eta 1 Mapped by PBA pathway IDA
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Mapped by significant region IDA
GJB6 gap junction protein, beta 6, 30kDa Mapped by significant region IDA
PECR peroxisomal trans-2-enoyl-CoA reductase Mapped by significant region IDA
RAD1 RAD1 homolog (S. pombe) Mapped by significant region IDA
TMED2 transmembrane emp24 domain trafficking protein 2 Mapped by CNV IDA
SCAMP2 secretory carrier membrane protein 2 Mapped by PBA pathway IDA
MTA3 metastasis associated 1 family, member 3 Mapped by Literature SNP IDA
THRAP3 thyroid hormone receptor associated protein 3 Mapped by PBA pathway IDA
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 Mapped by significant region TAS[8075637]
DPF2 D4, zinc and double PHD fingers family 2 Mapped by significant region IDA
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway IDA