ADHDgene Database

Gene Report

Basic Info

Approved Symbol	HECTD1
Symbol Alias	KIAA1131
Approved Name	HECT domain containing 1
Location	14q12
Position	chr14:31569324-31676689, -
External Links	HGNC: 20157 Entrez Gene: 25831 Ensembl: ENSG00000092148 UCSC: uc001wrc.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
14q12	chr14:24600000-33300000	1 (1/0/0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0046872	metal ion binding	Molecular Function		170
GO:0001843	neural tube closure	Biological Process		10
GO:0004842	ubiquitin-protein ligase activity	Molecular Function		52
GO:0005737	cytoplasm	Cellular Component		690
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological Process		16
GO:0005515	protein binding	Molecular Function	IPI[12421765]	910
GO:0005634	nucleus	Cellular Component		770

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with HECTD1 (count: 9)

Gene Symbol	Pathway Count	Pathway List
HERC2	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;
HERC5	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;
NEDD4L	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;
PARK2	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;
RCHY1	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;
TRIM32	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;
TRIP12	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;
UBE3A	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;
WWP1	5	ubiquitin-protein ligase activity; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; nucleus;

Genes shared at least 2 KEGG pathways with HECTD1 (count: 0)

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Region: chr14:31569324..31676689 View in gBrowse