ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TRIM13
Previous Symbol	RFP2
Symbol Alias	Leu5, RNF77, DLEU5
Approved Name	tripartite motif containing 13
Previous Name	ret finger protein 2, "tripartite motif-containing 13"
Location	13q14
Position	chr13:50570024-50594617, +
External Links	HGNC: 9976 Entrez Gene: 10206 Ensembl: ENSG00000204977 UCSC: uc001vdp.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 1)

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)

rs_ID	Location	Functional Annotation
rs2066550	Chr13:50590871(Fwd)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 17)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	IDA[17314412]	52
GO:0005737	cytoplasm	Cellular Component	IDA[11331580]	690
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IDA[17314412]	140
GO:0004871	signal transducer activity	Molecular Function	IMP[12761501]	49
GO:0005515	protein binding	Molecular Function		910
GO:0009653	anatomical structure morphogenesis	Biological Process	TAS[9599022]	26
GO:0010332	response to gamma radiation	Biological Process		3
GO:0007165	signal transduction	Biological Process	IMP[12761501]	171
GO:0008270	zinc ion binding	Molecular Function		323
GO:0016239	positive regulation of macroautophagy	Biological Process		2
GO:0030433	ER-associated protein catabolic process	Biological Process	IDA[17314412]	7
GO:0010942	positive regulation of cell death	Biological Process		3
GO:0016021	integral to membrane	Cellular Component		845
GO:0051865	protein autoubiquitination	Biological Process	IDA[17314412]	6
GO:0097038	perinuclear endoplasmic reticulum	Cellular Component		2
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process	IMP[12761501]	27
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IDA[17314412]	16

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TRIM13 (count: 17)

Gene Symbol	Pathway Count	Pathway List
PARK2	6	ubiquitin-protein ligase activity; cytoplasm; protein binding; zinc ion binding; protein autoubiquitination; positive regulation of I-kappaB kinase/NF-kappaB cascade;
BIRC2	5	ubiquitin-protein ligase activity; protein binding; zinc ion binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process;
BIRC3	5	ubiquitin-protein ligase activity; cytoplasm; protein binding; zinc ion binding; positive regulation of I-kappaB kinase/NF-kappaB cascade;
CBL	5	ubiquitin-protein ligase activity; cytoplasm; signal transducer activity; protein binding; zinc ion binding;
LRSAM1	5	ubiquitin-protein ligase activity; cytoplasm; protein binding; zinc ion binding; protein autoubiquitination;
MALT1	5	ubiquitin-protein ligase activity; cytoplasm; signal transducer activity; protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade;
RCHY1	5	ubiquitin-protein ligase activity; cytoplasm; protein binding; zinc ion binding; protein autoubiquitination;
RNF144B	5	ubiquitin-protein ligase activity; cytoplasm; protein binding; zinc ion binding; integral to membrane;
RNF31	5	ubiquitin-protein ligase activity; cytoplasm; protein binding; zinc ion binding; positive regulation of I-kappaB kinase/NF-kappaB cascade;
TRIM5	5	ubiquitin-protein ligase activity; cytoplasm; protein binding; zinc ion binding; positive regulation of I-kappaB kinase/NF-kappaB cascade;
WWP1	5	ubiquitin-protein ligase activity; cytoplasm; protein binding; signal transduction; proteasomal ubiquitin-dependent protein catabolic process;
NEK6	5	cytoplasm; signal transducer activity; protein binding; signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade;
PRKCB	5	cytoplasm; protein binding; signal transduction; zinc ion binding; positive regulation of I-kappaB kinase/NF-kappaB cascade;
TRAF1	5	cytoplasm; protein binding; signal transduction; zinc ion binding; positive regulation of I-kappaB kinase/NF-kappaB cascade;
GJA1	5	endoplasmic reticulum membrane; signal transducer activity; protein binding; signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade;
SYVN1	5	endoplasmic reticulum membrane; protein binding; zinc ion binding; ER-associated protein catabolic process; integral to membrane;
MAVS	5	signal transducer activity; protein binding; signal transduction; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade;

Genes shared at least 2 KEGG pathways with TRIM13 (count: 0)

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Region: chr13:50570024..50594617 View in gBrowse