ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RNF31
Symbol Alias	ZIBRA, FLJ10111, FLJ23501
Approved Name	ring finger protein 31
Location	14q11.2
Position	chr14:24616659-24629870, +
External Links	HGNC: 16031 Entrez Gene: 55072 Ensembl: ENSG00000092098 UCSC: uc001wmn.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
14q12	chr14:24600000-33300000	1 (1/0/0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0050852	T cell receptor signaling pathway	Biological Process		21
GO:0043130	ubiquitin binding	Molecular Function		9
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process		27
GO:0035631	CD40 receptor complex	Cellular Component		2
GO:0023035	CD40 signaling pathway	Biological Process		1
GO:0009898	internal side of plasma membrane	Cellular Component		8
GO:0008270	zinc ion binding	Molecular Function		323
GO:0005737	cytoplasm	Cellular Component		690
GO:0005515	protein binding	Molecular Function		910
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	IDA[17006537]	52
GO:0000209	protein polyubiquitination	Biological Process	IDA[17006537]	23
GO:0097039	protein linear polyubiquitination	Biological Process		1
GO:0051092	positive regulation of NF-kappaB transcription factor activity	Biological Process	IDA[19136968]	27
GO:0071797	LUBAC complex	Cellular Component		1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RNF31 (count: 14)

Gene Symbol	Pathway Count	Pathway List
TRIM32	7	ubiquitin binding; zinc ion binding; cytoplasm; protein binding; ubiquitin-protein ligase activity; protein polyubiquitination; positive regulation of NF-kappaB transcription factor activity;
BIRC2	7	positive regulation of I-kappaB kinase/NF-kappaB cascade; CD40 receptor complex; internal side of plasma membrane; zinc ion binding; protein binding; ubiquitin-protein ligase activity; protein polyubiquitination;
MALT1	6	T cell receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytoplasm; protein binding; ubiquitin-protein ligase activity; positive regulation of NF-kappaB transcription factor activity;
PARK2	6	positive regulation of I-kappaB kinase/NF-kappaB cascade; zinc ion binding; cytoplasm; protein binding; ubiquitin-protein ligase activity; protein polyubiquitination;
TRIM5	6	positive regulation of I-kappaB kinase/NF-kappaB cascade; zinc ion binding; cytoplasm; protein binding; ubiquitin-protein ligase activity; positive regulation of NF-kappaB transcription factor activity;
RELA	5	T cell receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytoplasm; protein binding; positive regulation of NF-kappaB transcription factor activity;
UBB	5	T cell receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein binding; protein polyubiquitination; positive regulation of NF-kappaB transcription factor activity;
UBC	5	T cell receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein binding; protein polyubiquitination; positive regulation of NF-kappaB transcription factor activity;
TNFAIP3	5	ubiquitin binding; zinc ion binding; cytoplasm; protein binding; ubiquitin-protein ligase activity;
BIRC3	5	positive regulation of I-kappaB kinase/NF-kappaB cascade; zinc ion binding; cytoplasm; protein binding; ubiquitin-protein ligase activity;
PRKCB	5	positive regulation of I-kappaB kinase/NF-kappaB cascade; zinc ion binding; cytoplasm; protein binding; positive regulation of NF-kappaB transcription factor activity;
TRAF1	5	positive regulation of I-kappaB kinase/NF-kappaB cascade; zinc ion binding; cytoplasm; protein binding; positive regulation of NF-kappaB transcription factor activity;
TRIM13	5	positive regulation of I-kappaB kinase/NF-kappaB cascade; zinc ion binding; cytoplasm; protein binding; ubiquitin-protein ligase activity;
LRSAM1	5	zinc ion binding; cytoplasm; protein binding; ubiquitin-protein ligase activity; protein polyubiquitination;

Genes shared at least 2 KEGG pathways with RNF31 (count: 0)

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Region: chr14:24616659..24629870 View in gBrowse