ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NDNL2
Symbol Alias	HCA4, MAGEG1, MAGEL3, NSE3, NSMCE3
Approved Name	necdin-like 2
Location	15q13.1
Position	chr15:29560353-29562033, -
External Links	HGNC: 7677 Entrez Gene: 56160 Ensembl: ENSG00000185115 UCSC: uc001zco.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 3)

ID	Location	Size	Band	Type
CNV_Williams[2010]_51	chr15:27000239-28153539 (NCBI Build 36.1 (hg18))	1153301	15q13.1-15q13.2	Gain
CNV_Williams[2010]_47	chr15:27013177-28153539 (NCBI Build 36.1 (hg18))	1140363	15q13.1-15q13.2	Gain
CNV_Jarick[2012]_29	chr15:27216380-28153539 (NCBI36 / hg18)	937160	15q13.1-15q13.2	dup

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
15q11.2-13.3	chr15:20700000-33600000	1 (1/0/0)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006310	DNA recombination	Biological Process		14
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0030915	Smc5-Smc6 complex	Cellular Component	IDA[18086888]	2
GO:0031398	positive regulation of protein ubiquitination	Biological Process		8
GO:0040008	regulation of growth	Biological Process		5
GO:0000781	chromosome, telomeric region	Cellular Component		9
GO:0005515	protein binding	Molecular Function		910
GO:0005634	nucleus	Cellular Component		770
GO:0005737	cytoplasm	Cellular Component		690
GO:0006281	DNA repair	Biological Process		62

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NDNL2 (count: 11)

Gene Symbol	Pathway Count	Pathway List
IGHMBP2	6	DNA recombination; regulation of transcription, DNA-dependent; protein binding; nucleus; cytoplasm; DNA repair;
INO80E	5	DNA recombination; regulation of transcription, DNA-dependent; protein binding; nucleus; DNA repair;
MRE11A	5	DNA recombination; chromosome, telomeric region; protein binding; nucleus; DNA repair;
NFRKB	5	DNA recombination; regulation of transcription, DNA-dependent; protein binding; nucleus; DNA repair;
SMC1A	5	DNA recombination; protein binding; nucleus; cytoplasm; DNA repair;
SMC2	5	DNA recombination; protein binding; nucleus; cytoplasm; DNA repair;
XRCC5	5	DNA recombination; protein binding; nucleus; cytoplasm; DNA repair;
PTTG1	5	regulation of transcription, DNA-dependent; protein binding; nucleus; cytoplasm; DNA repair;
SSRP1	5	regulation of transcription, DNA-dependent; protein binding; nucleus; cytoplasm; DNA repair;
TERF2IP	5	regulation of transcription, DNA-dependent; chromosome, telomeric region; protein binding; nucleus; cytoplasm;
TP53BP1	5	chromosome, telomeric region; protein binding; nucleus; cytoplasm; DNA repair;

Genes shared at least 2 KEGG pathways with NDNL2 (count: 0)

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Region: chr15:29560353..29562033 View in gBrowse