ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CDK20
Previous Symbol	CCRK
Symbol Alias	p42
Approved Name	cyclin-dependent kinase 20
Previous Name	"cell cycle related kinase"
Location	9q22.1
Position	chr9:90581356-90589668, -1
External Links	HGNC: 21420 Entrez Gene: 23552 Ensembl: ENSG00000156345 UCSC: uc004apr.3
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin; Mapped by significant region

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Hinney, A., 2011	This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08.	Non-significant

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs11142062	chr9:90658749(Fwd)		1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q22	chr9:90400000-102600000	3 (1/1/1)

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005929	cilium	cellular component	IEA	17
GO:0005515	protein binding	molecular function	IPI	1015
GO:0005524	ATP binding	molecular function	IEA	265
GO:0005737	cytoplasm	cellular component	IEA	781
GO:0004693	cyclin-dependent protein kinase activity	molecular function	IEA	5
GO:0051301	cell division	biological process	IEA	68
GO:0005634	nucleus	cellular component	IEA	877
GO:0007275	multicellular organismal development	biological process	IEA	79

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CDK20 (count: 5)

Gene Symbol	Pathway Count	Pathway List
SMC2	5	protein binding; ATP binding; cytoplasm; cell division; nucleus;
CCND3	5	protein binding; cytoplasm; cyclin-dependent protein kinase activity; cell division; nucleus;
UBE2I	5	protein binding; ATP binding; cytoplasm; cell division; nucleus;
SMC3	5	protein binding; ATP binding; cytoplasm; cell division; nucleus;
SMC1A	5	protein binding; ATP binding; cytoplasm; cell division; nucleus;

Genes shared at least 2 KEGG pathways with CDK20 (count: 0)

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Region: chr9:90581356..90589668 View in gBrowse