ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SMC2
Previous Symbol	SMC2L1
Symbol Alias	hCAP-E, CAP-E
Approved Name	structural maintenance of chromosomes 2
Previous Name	SMC2 (structural maintenance of chromosomes 2, yeast)-like 1, "SMC2 structural maintenance of chromosomes 2-like 1 (yeast)"
Location	9q31.1
Position	chr9:106856541-106903700, +
External Links	HGNC: 14011 Entrez Gene: 10592 Ensembl: ENSG00000136824 UCSC: uc004bbw.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)

Gene related GO terms (count: 16)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0046982	protein heterodimerization activity	Molecular Function	IPI[9789013]	68
GO:0045132	meiotic chromosome segregation	Biological Process		1
GO:0010032	meiotic chromosome condensation	Biological Process		1
GO:0007076	mitotic chromosome condensation	Biological Process	IDA[11136719]	5
GO:0051383	kinetochore organization	Biological Process		1
GO:0051301	cell division	Biological Process		58
GO:0005634	nucleus	Cellular Component	IDA[12589063]	770
GO:0005524	ATP binding	Molecular Function		228
GO:0005515	protein binding	Molecular Function	IPI[12589063]	910
GO:0000796	condensin complex	Cellular Component	IDA[10958694]	1
GO:0007062	sister chromatid cohesion	Biological Process		5
GO:0006310	DNA recombination	Biological Process		14
GO:0006281	DNA repair	Biological Process		62
GO:0005737	cytoplasm	Cellular Component	IDA[12589063]	690
GO:0000228	nuclear chromosome	Cellular Component	IDA[10958694]	4
GO:0000793	condensed chromosome	Cellular Component	IDA[12589063]	4

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SMC2 (count: 13)

Gene Symbol	Pathway Count	Pathway List
SMC1A	9	protein heterodimerization activity; cell division; nucleus; ATP binding; protein binding; sister chromatid cohesion; DNA recombination; DNA repair; cytoplasm;
SMC3	8	protein heterodimerization activity; cell division; nucleus; ATP binding; protein binding; sister chromatid cohesion; DNA repair; cytoplasm;
IGHMBP2	6	nucleus; ATP binding; protein binding; DNA recombination; DNA repair; cytoplasm;
XRCC5	6	nucleus; ATP binding; protein binding; DNA recombination; DNA repair; cytoplasm;
BARD1	5	protein heterodimerization activity; nucleus; protein binding; DNA repair; cytoplasm;
CDCA5	5	mitotic chromosome condensation; cell division; nucleus; protein binding; cytoplasm;
CDK20	5	cell division; nucleus; ATP binding; protein binding; cytoplasm;
CEP164	5	cell division; nucleus; protein binding; DNA repair; cytoplasm;
PTTG1	5	cell division; nucleus; protein binding; DNA repair; cytoplasm;
CHD1L	5	nucleus; ATP binding; protein binding; DNA repair; cytoplasm;
MRE11A	5	nucleus; protein binding; sister chromatid cohesion; DNA recombination; DNA repair;
NDNL2	5	nucleus; protein binding; DNA recombination; DNA repair; cytoplasm;
SMG1	5	nucleus; ATP binding; protein binding; DNA repair; cytoplasm;

Genes shared at least 2 KEGG pathways with SMC2 (count: 0)

View in gBrowse

Region: chr9:106856541..106903700 View in gBrowse