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- Data Summary
Gene Report
Approved Symbol | DHX8 |
---|---|
Previous Symbol | DDX8 |
Symbol Alias | HRH1, PRP22, PRPF22 |
Approved Name | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
Previous Name | DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 8 (RNA helicase) |
Location | 17q21.31 |
Position | chr17:41561334-41601680, + |
External Links |
HGNC: 2749 Entrez Gene: 1659 Ensembl: ENSG00000067596 UCSC: uc002idu.1 |
No. of Studies | 0 (significant: 0; non-significant: 0; trend: 0) |
Source | Mapped by PBA pathway |
GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)
ID | Name | Type | Evidence[PMID] | No. of Genes in ADHDgene |
---|---|---|---|---|
GO:0005681 | spliceosomal complex | Cellular Component | TAS[7935475] | 51 |
GO terms by database search (count: 10)
ID | Name | Type | Evidence[PMID] | No. of Genes in ADHDgene |
---|---|---|---|---|
GO:0005634 | nucleus | Cellular Component | 770 | |
GO:0005524 | ATP binding | Molecular Function | 228 | |
GO:0005730 | nucleolus | Cellular Component | 243 | |
GO:0003723 | RNA binding | Molecular Function | 104 | |
GO:0000398 | mRNA splicing, via spliceosome | Biological Process | IC[11991638] | 54 |
GO:0005515 | protein binding | Molecular Function | IPI[16820410] | 910 |
GO:0004004 | ATP-dependent RNA helicase activity | Molecular Function | TAS[7935475] | 5 |
GO:0006396 | RNA processing | Biological Process | TAS[7935475] | 11 |
GO:0008380 | RNA splicing | Biological Process | TAS[7935475] | 65 |
GO:0071013 | catalytic step 2 spliceosome | Cellular Component | IDA[11991638] | 31 |
ID | Name | No. of Genes in ADHDgene | Brief Description |
---|---|---|---|
hsa03040 | Spliceosome | 47 | After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More... |
Region: chr17:41561334..41601680 View in gBrowse
Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014