ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DDX54
Symbol Alias	MGC2835, APR-5, DP97
Approved Name	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Location	12q24.11
Position	chr12:113594978-113623284, -
External Links	HGNC: 20084 Entrez Gene: 79039 Ensembl: ENSG00000123064 UCSC: uc001tuq.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0035257	nuclear hormone receptor binding	Molecular Function		30

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005730	nucleolus	Cellular Component	IDA[12466272]	243
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0005524	ATP binding	Molecular Function		228
GO:0005634	nucleus	Cellular Component	IDA[12466272]	770
GO:0016070	RNA metabolic process	Biological Process	IDA[12466272]	46
GO:0030331	estrogen receptor binding	Molecular Function	IDA[12466272]	10
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0006396	RNA processing	Biological Process	IDA[12466272]	11
GO:0030520	intracellular estrogen receptor signaling pathway	Biological Process	TAS[12466272]	4
GO:0003723	RNA binding	Molecular Function		104
GO:0003714	transcription corepressor activity	Molecular Function	IDA[12466272]	29
GO:0005102	receptor binding	Molecular Function	IDA[12466272]	61
GO:0004004	ATP-dependent RNA helicase activity	Molecular Function	IDA[12466272]	5

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DDX54 (count: 13)

Gene Symbol	Pathway Count	Pathway List
DHX8	6	nucleolus; ATP binding; nucleus; RNA processing; RNA binding; ATP-dependent RNA helicase activity;
SF1	6	nucleolus; transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; RNA binding; transcription corepressor activity;
DAXX	5	nucleolus; transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; nuclear hormone receptor binding;
HSPA8	5	nucleolus; transcription, DNA-dependent; ATP binding; nucleus; RNA metabolic process;
NCOA6	5	nucleolus; nucleus; estrogen receptor binding; intracellular estrogen receptor signaling pathway; nuclear hormone receptor binding;
PSPC1	5	nucleolus; transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; RNA binding;
SETD1A	5	nucleolus; transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; RNA binding;
ZNF74	5	nucleolus; transcription, DNA-dependent; nucleus; regulation of transcription, DNA-dependent; RNA binding;
CNOT6	5	transcription, DNA-dependent; nucleus; RNA metabolic process; regulation of transcription, DNA-dependent; RNA binding;
IGHMBP2	5	transcription, DNA-dependent; ATP binding; nucleus; regulation of transcription, DNA-dependent; RNA binding;
NRIP1	5	transcription, DNA-dependent; nucleus; estrogen receptor binding; nuclear hormone receptor binding; transcription corepressor activity;
NSD1	5	transcription, DNA-dependent; nucleus; estrogen receptor binding; nuclear hormone receptor binding; transcription corepressor activity;
PPARGC1B	5	nucleus; estrogen receptor binding; intracellular estrogen receptor signaling pathway; nuclear hormone receptor binding; RNA binding;

Genes shared at least 2 KEGG pathways with DDX54 (count: 0)

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Region: chr12:113594978..113623284 View in gBrowse