ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005102
Name	receptor binding
Type	Molecular Function
No. of Genes in ADHDgene	61
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 61)

Literature-origin genes (count: 10)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
NTF3	neurotrophin 3	12p13	3(1/2/0)	TAS[2236018]
NRXN1	neurexin 1	2p16.3	1(0/1/0)
NXPH1	neurexophilin 1	7p22	1(0/1/0)
NPPC	natriuretic peptide C	2q24-qter	1(0/1/0)	IPI[1660465]
LPL	lipoprotein lipase	8p22	1(0/0/1)	IPI[10085125]
PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B	17	1(0/1/0)
ARRB2	arrestin, beta 2	17p13	1(1/0/0)	IPI[18604210]
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)
CNTFR	ciliary neurotrophic factor receptor	9p13	1(1/0/0)	IPI[12707266]
GDNF	glial cell derived neurotrophic factor	5p13.1-p12	2(1/1/0)	TAS[10829012]

Genes from other sources (count: 51)

Approved Symbol	Approved Name	Source	Evidence[PMID]
ANGPTL5	angiopoietin-like 5	Mapped by significant region
C5	complement component 5	Mapped by significant region	TAS[9590258]
ANGPTL2	angiopoietin-like 2	Mapped by significant region
RCHY1	ring finger and CHY zinc finger domain containing 1	Mapped by CNV
PAOX	polyamine oxidase (exo-N4-amino)	Mapped by CNV
RASA1	RAS p21 protein activator (GTPase activating protein) 1	Mapped by PBA pathway	IPI[2157284]
LAMA3	laminin, alpha 3	Mapped by significant region
MLYCD	malonyl-CoA decarboxylase	Mapped by CNV; Mapped by significant region
NUDT7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	Mapped by significant region
NMU	neuromedin U	Mapped by LD-proxy	TAS[10811630]
MAP7	microtubule-associated protein 7	Mapped by PBA pathway; Mapped by significant region
CTNND1	catenin (cadherin-associated protein), delta 1	Mapped by significant region	IPI[19332538]
PECR	peroxisomal trans-2-enoyl-CoA reductase	Mapped by significant region	IPI[11669066]
TIGIT	T cell immunoreceptor with Ig and ITIM domains	Mapped by LD-proxy	IPI[19011627]
CNTNAP2	contactin associated protein-like 2	Mapped by CNV
PRDX5	peroxiredoxin 5	Mapped by significant region
TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	Mapped by significant region	TAS[7913952]
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	Mapped by PBA pathway	IPI[14701856]
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	Mapped by significant region	TAS[8391931]
MPV17L	MPV17 mitochondrial membrane protein-like	Mapped by CNV; Mapped by significant region
PANX1	pannexin 1	Mapped by significant region	IPI[17036048]
F7	coagulation factor VII (serum prothrombin conversion accelerator)	Mapped by CNV
CNTNAP4	contactin associated protein-like 4	Mapped by significant region
INHA	inhibin, alpha	Mapped by significant region	IPI[9032295]
UFD1L	ubiquitin fusion degradation 1 like (yeast)	Mapped by CNV
FYB	FYN binding protein	Mapped by significant region	TAS[10747096]
DDX54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	Mapped by PBA pathway	IDA[12466272]
GLG1	golgi glycoprotein 1	Mapped by significant region	TAS[7531823]
PTPRD	protein tyrosine phosphatase, receptor type, D	Mapped by CNV
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mapped by CNV	IPI[12782713]
AMACR	alpha-methylacyl-CoA racemase	Mapped by significant region	IPI[11060344]
CADM1	cell adhesion molecule 1	Mapped by significant region	IPI[15811952]; ISS[12826663]
TNFSF18	tumor necrosis factor (ligand) superfamily, member 18	Mapped by significant region	TAS[10074428]
PGR	progesterone receptor	Mapped by significant region	IPI[12771131]
AKAP6	A kinase (PRKA) anchor protein 6	Mapped by significant region	IPI[10830164]
CLCF1	cardiotrophin-like cytokine factor 1	Mapped by significant region	IPI[15272019]
NCK1	NCK adaptor protein 1	Mapped by PBA pathway	IPI[12110186]
TRDN	triadin	Mapped by significant region
LAMA2	laminin, alpha 2	Mapped by CNV; Mapped by significant region
GRP	gastrin-releasing peptide	Mapped by significant region	NAS[3027901]
TNFSF15	tumor necrosis factor (ligand) superfamily, member 15	Mapped by significant region	TAS[9434163]
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	Mapped by significant region	IDA[11254688]
MFAP4	microfibrillar-associated protein 4	Mapped by significant region
CRTAM	cytotoxic and regulatory T cell molecule	Mapped by significant region	IPI[15811952]
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	Mapped by significant region
TNR	tenascin R (restrictin, janusin)	Mapped by significant region
C1QTNF2	C1q and tumor necrosis factor related protein 2	Mapped by significant region
PLA2G1B	phospholipase A2, group IB (pancreas)	Mapped by PBA pathway	IDA[1918029]; IPI[7721806]
NPY	neuropeptide Y	Mapped by CNV; Mapped by significant region	TAS[8132547]
TNC	tenascin C	Mapped by significant region
CXCL12	chemokine (C-X-C motif) ligand 12	Mapped by PBA pathway	TAS[10438529]