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Large-scale studies
- Genome-wide Association Studies of ADHD
- Genome-wide Linkage Studies of ADHD
- Genome-wide CNV Analyses of ADHD
- Meta-analysis Studies of ADHD
Data Summary
GO Report
ID | GO:0035257 |
---|---|
Name | nuclear hormone receptor binding |
Type | molecular function |
No. of Genes in ADHDgene | 5 |
Source | Pathway by PBA (with statistical significance of FDR<0.05) |
Data Set Reference | Gene Set | Mapping Rule | P-value | FDR | Result Link |
---|---|---|---|---|---|
Neale BM, 2008 | MsigDB 3.0 c5.mf | 500kb upstream and downstream of gene | 0.004 | 0.04475 | Link |
PMID | Citation | Comment |
---|---|---|
15579758 | Vermiglio F, Lo Presti VP, et al.Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild-moderate iodine deficiency: A possible novel iodine deficiency disorder in developed countries. J Clin Endocrinol Metab 2004, 89(12):6054-6060. | So far, a similar prevalence of ADHD has been reported only ...... So far, a similar prevalence of ADHD has been reported only in children with generalized resistance to thyroid hormones. This might suggest a common ADHD pathogenetic mechanism consisting either of reduced sensitivity of the nuclear receptors to thyroid hormone ( generalized resistance to thyroid hormones) or reduced availability of intracellular T-3 for nuclear receptor binding. More... |