ADHDgene Database

Gene Report

Basic Info

Approved Symbol	OASL
Symbol Alias	TRIP14, p59OASL
Approved Name	2'-5'-oligoadenylate synthetase-like
Location	12q24.2
Position	chr12:121458095-121477045, -
External Links	HGNC: 8090 Entrez Gene: 8638 Ensembl: ENSG00000135114 UCSC: uc001tzj.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 16)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0035257	nuclear hormone receptor binding	Molecular Function		30

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003677	DNA binding	Molecular Function	IDA[9826176]	220
GO:0001730	2'-5'-oligoadenylate synthetase activity	Molecular Function	IDA[9826176]	1
GO:0045071	negative regulation of viral genome replication	Biological Process	IDA[18931074]	4
GO:0046966	thyroid hormone receptor binding	Molecular Function	TAS[7776974]	18
GO:0051607	defense response to virus	Biological Process		15
GO:0060333	interferon-gamma-mediated signaling pathway	Biological Process		8
GO:0060337	type I interferon-mediated signaling pathway	Biological Process		5
GO:0003725	double-stranded RNA binding	Molecular Function	IDA[9826176]	6
GO:0005524	ATP binding	Molecular Function		228
GO:0005730	nucleolus	Cellular Component	IDA[9826176]	243
GO:0005737	cytoplasm	Cellular Component	IDA[9826176]	690
GO:0005829	cytosol	Cellular Component		447
GO:0008150	biological_process	Biological Process		106
GO:0009615	response to virus	Biological Process		21
GO:0019221	cytokine-mediated signaling pathway	Biological Process		28

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with OASL (count: 6)

Gene Symbol	Pathway Count	Pathway List
IRF7	7	DNA binding; interferon-gamma-mediated signaling pathway; type I interferon-mediated signaling pathway; cytoplasm; cytosol; response to virus; cytokine-mediated signaling pathway;
RNASEL	6	negative regulation of viral genome replication; defense response to virus; type I interferon-mediated signaling pathway; ATP binding; cytosol; cytokine-mediated signaling pathway;
IRF9	6	defense response to virus; interferon-gamma-mediated signaling pathway; type I interferon-mediated signaling pathway; cytoplasm; cytosol; cytokine-mediated signaling pathway;
DHX9	5	DNA binding; double-stranded RNA binding; ATP binding; nucleolus; cytoplasm;
MAPK1	5	DNA binding; ATP binding; nucleolus; cytoplasm; cytosol;
RELA	5	DNA binding; defense response to virus; cytoplasm; cytosol; cytokine-mediated signaling pathway;

Genes shared at least 2 KEGG pathways with OASL (count: 0)

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Region: chr12:121458095..121477045 View in gBrowse