ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	NCOA7
Symbol Alias	ERAP140, dJ187J11.3
Approved Name	nuclear receptor coactivator 7
Location	6q22.33
Position	chr6:126102307-126252266, +
External Links	HGNC: 21081 Entrez Gene: 135112 Ensembl: ENSG00000111912 UCSC: uc003qai.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 8)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0035257	nuclear hormone receptor binding	Molecular Function	IDA[11971969]	30

GO terms by database search (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[11971969]	131
GO:0016998	cell wall macromolecule catabolic process	Biological Process		1
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	Molecular Function	IDA[11971969]	19
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0005634	nucleus	Cellular Component		770
GO:0005622	intracellular	Cellular Component		67
GO:0005515	protein binding	Molecular Function		910

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NCOA7 (count: 8)

Gene Symbol	Pathway Count	Pathway List
HMGA1	5	nuclear hormone receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; nucleus; protein binding;
MED1	5	nuclear hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; protein binding;
NCOA6	5	nuclear hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; protein binding;
NRIP1	5	nuclear hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; nucleus; protein binding;
SMARCD3	5	nuclear hormone receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; nucleus; protein binding;
THRAP3	5	nuclear hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; protein binding;
KDM1A	5	positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; nucleus; protein binding;
SS18	5	positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; nucleus; protein binding;

Genes shared at least 2 KEGG pathways with NCOA7 (count: 0)

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Region: chr6:126102307..126252266 View in gBrowse