ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	NUP62
Symbol Alias	p62, DKFZp547L134, IBSN, SNDI, MGC841, FLJ20822, FLJ43869
Approved Name	nucleoporin 62kDa
Previous Name	"nucleoporin 62kD"
Name Alias	"nuclear pore glycoprotein p62"
Location	19q13.33
Position	chr19:50410082-50433020, -1
External Links	HGNC: 8066 Entrez Gene: 23636 Ensembl: ENSG00000213024 UCSC: uc002pqx.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 40)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 40)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043069	negative regulation of programmed cell death	biological process	IDA[11244088]; ISS	4
GO:0009966	regulation of signal transduction	biological process	NAS[8702753]	4
GO:0015758	glucose transport	biological process	TAS	14
GO:0006913	nucleocytoplasmic transport	biological process	NAS[8589458]	3
GO:0043130	ubiquitin binding	molecular function	IDA[8702753]; ISS	9
GO:0005635	nuclear envelope	cellular component	IDA; TAS	22
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	biological process	NAS[11244088]	1
GO:0030159	receptor signaling complex scaffold activity	molecular function	IDA[11244088]; ISS	8
GO:0005487	nucleocytoplasmic transporter activity	molecular function	NAS[8589458]	3
GO:0046930	pore complex	cellular component	NAS[15175862]	1
GO:0016032	viral reproduction	biological process	TAS	66
GO:0055085	transmembrane transport	biological process	TAS	95
GO:0051028	mRNA transport	biological process	IEA	8
GO:0030529	ribonucleoprotein complex	cellular component	IDA[18809582]	24
GO:0008645	hexose transport	biological process	TAS	7
GO:0005515	protein binding	molecular function	IPI	1015
GO:0005737	cytoplasm	cellular component	NAS[10373430]	781
GO:0046966	thyroid hormone receptor binding	molecular function	IPI[15625236]; ISS	17
GO:0009755	hormone-mediated signaling pathway	biological process	NAS[15625236]	4
GO:0007166	cell surface receptor signaling pathway	biological process	IDA[10799545]; ISS; NAS[10373430]	36
GO:0046578	regulation of Ras protein signal transduction	biological process	NAS[11553620]	3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	biological process	IDA[10356400]; ISS	28
GO:0042169	SH2 domain binding	molecular function	IDA[8650207]; ISS	8
GO:0005643	nuclear pore	cellular component	IDA[1915414]; ISS	11
GO:0010827	regulation of glucose transport	biological process	TAS	4
GO:0008285	negative regulation of cell proliferation	biological process	IDA[11013214]; ISS	65
GO:0017056	structural constituent of nuclear pore	molecular function	IEA	2
GO:0003682	chromatin binding	molecular function	NAS[11852044]	50
GO:0008219	cell death	biological process	IMP[11244088]; ISS	33
GO:0006351	transcription, DNA-dependent	biological process	IDA[10373430]; ISS	281
GO:0000922	spindle pole	cellular component	IEA	22
GO:0015031	protein transport	biological process	IEA	89
GO:0044281	small molecule metabolic process	biological process	TAS	270
GO:0043231	intracellular membrane-bounded organelle	cellular component	IDA	65
GO:0031074	nucleocytoplasmic shuttling complex	cellular component	NAS[8589458]	1
GO:0005975	carbohydrate metabolic process	biological process	TAS	59
GO:0045893	positive regulation of transcription, DNA-dependent	biological process	IDA[15625236]; ISS	89
GO:0043066	negative regulation of apoptotic process	biological process	IDA[11755531]; ISS	85
GO:0019221	cytokine-mediated signaling pathway	biological process	TAS	33
GO:0031965	nuclear membrane	cellular component	IDA	27

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NUP62 (count: 30)

Gene Symbol	Pathway Count	Pathway List
NUP160	13	glucose transport; nuclear envelope; nucleocytoplasmic transporter activity; viral reproduction; transmembrane transport; hexose transport; protein binding; nuclear pore; regulation of glucose transport; protein transport; small molecule metabolic process; carbohydrate metabolic process; cytokine-mediated signaling pathway;
NUP155	12	glucose transport; nuclear envelope; viral reproduction; transmembrane transport; hexose transport; nuclear pore; regulation of glucose transport; structural constituent of nuclear pore; small molecule metabolic process; carbohydrate metabolic process; cytokine-mediated signaling pathway; nuclear membrane;
NUPL2	11	glucose transport; viral reproduction; transmembrane transport; mRNA transport; hexose transport; nuclear pore; regulation of glucose transport; small molecule metabolic process; carbohydrate metabolic process; cytokine-mediated signaling pathway; nuclear membrane;
XPO1	7	nuclear envelope; viral reproduction; mRNA transport; ribonucleoprotein complex; protein binding; cytoplasm; nuclear pore;
RELA	7	protein binding; cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; chromatin binding; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; cytokine-mediated signaling pathway;
HK1	6	glucose transport; transmembrane transport; hexose transport; protein binding; small molecule metabolic process; carbohydrate metabolic process;
RAN	6	viral reproduction; protein binding; cytoplasm; nuclear pore; chromatin binding; positive regulation of transcription, DNA-dependent;
MVP	6	mRNA transport; ribonucleoprotein complex; protein binding; cytoplasm; nuclear pore; protein transport;
MED1	6	protein binding; thyroid hormone receptor binding; chromatin binding; small molecule metabolic process; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process;
NCOA6	6	protein binding; thyroid hormone receptor binding; chromatin binding; small molecule metabolic process; intracellular membrane-bounded organelle; positive regulation of transcription, DNA-dependent;
KANK2	5	negative regulation of programmed cell death; protein binding; cytoplasm; negative regulation of cell proliferation; transcription, DNA-dependent;
SLC2A3	5	glucose transport; transmembrane transport; hexose transport; small molecule metabolic process; carbohydrate metabolic process;
SLC37A4	5	glucose transport; transmembrane transport; hexose transport; small molecule metabolic process; carbohydrate metabolic process;
AXIN1	5	nucleocytoplasmic transport; protein binding; cytoplasm; cell death; positive regulation of transcription, DNA-dependent;
BNIP3	5	nuclear envelope; protein binding; cytoplasm; cell death; negative regulation of apoptotic process;
MMS19	5	receptor signaling complex scaffold activity; protein binding; cytoplasm; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
RCC1	5	viral reproduction; protein binding; cytoplasm; chromatin binding; nuclear membrane;
XRCC5	5	viral reproduction; protein binding; cytoplasm; transcription, DNA-dependent; negative regulation of apoptotic process;
UBC	5	viral reproduction; protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; cytokine-mediated signaling pathway;
HMGA1	5	viral reproduction; protein binding; negative regulation of cell proliferation; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
UBB	5	viral reproduction; protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; cytokine-mediated signaling pathway;
IGHMBP2	5	ribonucleoprotein complex; protein binding; cytoplasm; cell death; transcription, DNA-dependent;
SMARCD3	5	protein binding; cytoplasm; transcription, DNA-dependent; small molecule metabolic process; positive regulation of transcription, DNA-dependent;
APBB1	5	protein binding; cytoplasm; chromatin binding; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent;
ATXN1	5	protein binding; cytoplasm; cell death; transcription, DNA-dependent; intracellular membrane-bounded organelle;
CREBBP	5	protein binding; cytoplasm; chromatin binding; small molecule metabolic process; positive regulation of transcription, DNA-dependent;
BIRC2	5	protein binding; cell surface receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; negative regulation of apoptotic process;
INPPL1	5	protein binding; cytoplasm; SH2 domain binding; negative regulation of cell proliferation; small molecule metabolic process;
BIRC3	5	protein binding; cytoplasm; cell surface receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of apoptotic process;
MEN1	5	protein binding; cytoplasm; negative regulation of cell proliferation; chromatin binding; transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with NUP62 (count: 0)

View in gBrowse

Region: chr19:50410082..50433020 View in gBrowse