ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NUPL2
Symbol Alias	NLP_1, CG1, hCG1, H_RG271G13.9
Approved Name	nucleoporin like 2
Name Alias	"nucleoporin-like protein 1"
Location	7p15
Position	chr7:23221446-23240630, 1
External Links	HGNC: 17010 Entrez Gene: 11097 Ensembl: ENSG00000136243 UCSC: uc003svu.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Lesch[2011]_6	chr7:23010000-26070000 (NCBI Build 35 (hg17))	3060000	7p15.2-7p15.3	Duplication	Paternal (affected)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
7p15	chr7:20900000-28800000	2 (1/1/0)

Gene related GO terms (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0031965	nuclear membrane	cellular component	IEA	27
GO:0003676	nucleic acid binding	molecular function	IEA	46
GO:0010827	regulation of glucose transport	biological process	TAS	4
GO:0005829	cytosol	cellular component	TAS	485
GO:0051028	mRNA transport	biological process	IEA	8
GO:0005634	nucleus	cellular component	TAS[10358091]	877
GO:0044281	small molecule metabolic process	biological process	TAS	270
GO:0055085	transmembrane transport	biological process	TAS	95
GO:0006611	protein export from nucleus	biological process	TAS[10358091]	5
GO:0008645	hexose transport	biological process	TAS	7
GO:0005643	nuclear pore	cellular component	IEA	11
GO:0005975	carbohydrate metabolic process	biological process	TAS	59
GO:0005049	nuclear export signal receptor activity	molecular function	TAS[10358091]	1
GO:0016032	viral reproduction	biological process	TAS	66
GO:0019221	cytokine-mediated signaling pathway	biological process	TAS	33
GO:0015758	glucose transport	biological process	TAS	14
GO:0008270	zinc ion binding	molecular function	IEA	367

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NUPL2 (count: 7)

Gene Symbol	Pathway Count	Pathway List
NUP62	11	nuclear membrane; regulation of glucose transport; mRNA transport; small molecule metabolic process; transmembrane transport; hexose transport; nuclear pore; carbohydrate metabolic process; viral reproduction; cytokine-mediated signaling pathway; glucose transport;
NUP155	10	nuclear membrane; regulation of glucose transport; small molecule metabolic process; transmembrane transport; hexose transport; nuclear pore; carbohydrate metabolic process; viral reproduction; cytokine-mediated signaling pathway; glucose transport;
NUP160	10	regulation of glucose transport; cytosol; small molecule metabolic process; transmembrane transport; hexose transport; nuclear pore; carbohydrate metabolic process; viral reproduction; cytokine-mediated signaling pathway; glucose transport;
HK1	7	cytosol; nucleus; small molecule metabolic process; transmembrane transport; hexose transport; carbohydrate metabolic process; glucose transport;
XPO1	5	cytosol; mRNA transport; protein export from nucleus; nuclear pore; viral reproduction;
SLC2A3	5	small molecule metabolic process; transmembrane transport; hexose transport; carbohydrate metabolic process; glucose transport;
SLC37A4	5	small molecule metabolic process; transmembrane transport; hexose transport; carbohydrate metabolic process; glucose transport;

Genes shared at least 2 KEGG pathways with NUPL2 (count: 0)

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Region: chr7:23221446..23240630 View in gBrowse