ADHDgene Database

Gene Report

Basic Info

Approved Symbol	MVP
Symbol Alias	LRP, VAULT1
Approved Name	major vault protein
Location	16p11.2
Position	chr16:29831729-29859355, +
External Links	HGNC: 7531 Entrez Gene: 9961 Ensembl: ENSG00000013364 UCSC: uc002dui.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 4)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_16	chr16:29563594-30367556 (NCBI Build 36.1 (hg18))	803963	16p11.2	Loss
CNV_Williams[2010]_34	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813248	16p11.2	Loss	De novo
CNV_Williams[2010]_39	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813247	16p11.2	Gain
CNV_Jarick[2012]_35	chr16:29554843-30085308 (NCBI36 / hg18)	530466	16p11.2	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005515	protein binding	Molecular Function	IPI[18809583]	910
GO:0042493	response to drug	Biological Process	TAS[7585126]	68
GO:0030529	ribonucleoprotein complex	Cellular Component		23
GO:0070062	extracellular vesicular exosome	Cellular Component		7
GO:0051028	mRNA transport	Biological Process		8
GO:0005643	nuclear pore	Cellular Component		9
GO:0005634	nucleus	Cellular Component	TAS[7585126]	770
GO:0015031	protein transport	Biological Process		75
GO:0005737	cytoplasm	Cellular Component		690

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MVP (count: 3)

Gene Symbol	Pathway Count	Pathway List
NUP62	6	protein binding; ribonucleoprotein complex; mRNA transport; nuclear pore; protein transport; cytoplasm;
XPO1	6	protein binding; response to drug; ribonucleoprotein complex; mRNA transport; nuclear pore; cytoplasm;
GSK3B	5	protein binding; response to drug; ribonucleoprotein complex; nucleus; cytoplasm;

Genes shared at least 2 KEGG pathways with MVP (count: 0)

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Region: chr16:29831729..29859355 View in gBrowse