ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SF1
Previous Symbol	ZNF162
Symbol Alias	ZFM1
Approved Name	splicing factor 1
Previous Name	zinc finger protein 162
Location	11q13
Position	chr11:64532076-64546316, -
External Links	HGNC: 12950 Entrez Gene: 7536 Ensembl: ENSG00000168066 UCSC: uc001obb.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 17)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	Cellular Component	IDA[9731529]	51

GO terms by database search (count: 16)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005840	ribosome	Cellular Component	NAS[8752089]	12
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0008270	zinc ion binding	Molecular Function		323
GO:0022402	cell cycle process	Biological Process		2
GO:0030238	male sex determination	Biological Process		2
GO:0033327	Leydig cell differentiation	Biological Process		2
GO:0050810	regulation of steroid biosynthetic process	Biological Process		2
GO:0000389	mRNA 3'-splice site recognition	Biological Process	TAS[15647371]	5
GO:0000398	mRNA splicing, via spliceosome	Biological Process	IC[9731529]	54
GO:0003676	nucleic acid binding	Molecular Function		41
GO:0000245	spliceosomal complex assembly	Biological Process	NAS[8752089]	8
GO:0003714	transcription corepressor activity	Molecular Function	TAS[9660765]	29
GO:0003723	RNA binding	Molecular Function	TAS[8752089]	104
GO:0005634	nucleus	Cellular Component	NAS[7912130]	770
GO:0005730	nucleolus	Cellular Component		243

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SF1 (count: 29)

Gene Symbol	Pathway Count	Pathway List
SF3A3	7	zinc ion binding; mRNA 3'-splice site recognition; mRNA splicing, via spliceosome; nucleic acid binding; nucleus; spliceosomal complex; nucleolus;
BCL11A	6	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; nucleic acid binding; transcription corepressor activity; nucleus;
DDX54	6	transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription corepressor activity; RNA binding; nucleus; nucleolus;
ZNF74	6	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; RNA binding; nucleus; nucleolus;
SLU7	6	zinc ion binding; mRNA 3'-splice site recognition; mRNA splicing, via spliceosome; nucleus; spliceosomal complex; nucleolus;
U2AF1	6	zinc ion binding; mRNA splicing, via spliceosome; RNA binding; nucleus; spliceosomal complex; nucleolus;
SF3A1	6	mRNA 3'-splice site recognition; mRNA splicing, via spliceosome; RNA binding; nucleus; spliceosomal complex; nucleolus;
DPF2	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; nucleus; nucleolus;
HINFP	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; nucleus; nucleolus;
IGHMBP2	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; RNA binding; nucleus;
PSPC1	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; RNA binding; nucleus; nucleolus;
SETD1A	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; RNA binding; nucleus; nucleolus;
TRIM22	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; transcription corepressor activity; nucleus;
ZBTB34	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; nucleus; nucleolus;
ZBTB9	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; nucleus; nucleolus;
ZFP62	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; nucleic acid binding; nucleus;
ZNF263	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; nucleus; nucleolus;
ZNF77	5	transcription, DNA-dependent; regulation of transcription, DNA-dependent; zinc ion binding; nucleus; nucleolus;
FUS	5	zinc ion binding; mRNA splicing, via spliceosome; RNA binding; nucleus; nucleolus;
SF3A2	5	zinc ion binding; mRNA 3'-splice site recognition; mRNA splicing, via spliceosome; nucleic acid binding; spliceosomal complex;
ZMAT5	5	zinc ion binding; nucleic acid binding; nucleus; spliceosomal complex; nucleolus;
DDX23	5	mRNA splicing, via spliceosome; nucleic acid binding; nucleus; spliceosomal complex; nucleolus;
DHX8	5	mRNA splicing, via spliceosome; RNA binding; nucleus; spliceosomal complex; nucleolus;
HNRNPA1	5	mRNA splicing, via spliceosome; RNA binding; nucleus; spliceosomal complex; nucleolus;
HNRNPA2B1	5	mRNA splicing, via spliceosome; RNA binding; nucleus; spliceosomal complex; nucleolus;
PRPF6	5	mRNA splicing, via spliceosome; spliceosomal complex assembly; RNA binding; nucleus; spliceosomal complex;
SF3B2	5	mRNA splicing, via spliceosome; nucleic acid binding; nucleus; spliceosomal complex; nucleolus;
SNRNP200	5	mRNA splicing, via spliceosome; nucleic acid binding; nucleus; spliceosomal complex; nucleolus;
SNW1	5	mRNA splicing, via spliceosome; transcription corepressor activity; nucleus; spliceosomal complex; nucleolus;

Genes shared at least 2 KEGG pathways with SF1 (count: 0)

View in gBrowse

Region: chr11:64532076..64546316 View in gBrowse