ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CELF1
Previous Symbol	CUGBP1
Symbol Alias	CUG-BP, hNab50, BRUNOL2, NAB50, CUGBP, NAPOR, EDEN-BP
Approved Name	CUGBP, Elav-like family member 1
Previous Name	CUG triplet repeat, RNA-binding protein 1, "CUG triplet repeat, RNA binding protein 1"
Name Alias	CUG RNA-binding protein, "nuclear polyadenylated RNA-binding protein, 50-kD", "bruno-like 2", "embryo deadenylation element binding protein"
Location	11p11
Position	chr11:47487489-47587121, -
External Links	HGNC: 2549 Entrez Gene: 10658 Ensembl: ENSG00000149187 UCSC: uc001nfl.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 6)

Literature-origin SNPs (count: 0)

LD-proxies (count: 6)

rs_ID	Location	Functional Annotation
rs4752783	Chr11:47558220(Fwd)	intron_variant
rs4752839	Chr11:47495202(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant
rs1044269	Chr11:47487740(Fwd)	3_prime_UTR_variant; downstream_gene_variant
rs9666924	Chr11:47540007(Fwd)	intron_variant; upstream_gene_variant
rs4752843	Chr11:47531884(Fwd)	downstream_gene_variant; intron_variant
rs11819955	Chr11:47539208(Fwd)	intron_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043484	regulation of RNA splicing	Biological Process	IDA[16946708]	4
GO:0042835	BRE binding	Molecular Function	IDA[10893231]	2
GO:0040018	positive regulation of multicellular organism growth	Biological Process		6
GO:0031369	translation initiation factor binding	Molecular Function		2
GO:0030529	ribonucleoprotein complex	Cellular Component	NAS[10893231]	23
GO:0016246	RNA interference	Biological Process	NAS[10893231]	2
GO:0003723	RNA binding	Molecular Function	IDA[16946708]	104
GO:0003729	mRNA binding	Molecular Function	IDA[14726956]	10
GO:0000166	nucleotide binding	Molecular Function		73
GO:0000900	translation repressor activity, nucleic acid binding	Molecular Function	NAS[10893231]	2
GO:0007286	spermatid development	Biological Process		11
GO:0009790	embryo development	Biological Process	NAS[10893231]	17
GO:0006397	mRNA processing	Biological Process	TAS[8948631]	50
GO:0007281	germ cell development	Biological Process	NAS[10893231]	7
GO:0005737	cytoplasm	Cellular Component		690
GO:0006376	mRNA splice site selection	Biological Process		2
GO:0005515	protein binding	Molecular Function	IPI[16946708]	910
GO:0005634	nucleus	Cellular Component	NAS[10893231]	770

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CELF1 (count: 22)

Gene Symbol	Pathway Count	Pathway List
CELF4	9	BRE binding; mRNA binding; nucleotide binding; translation repressor activity, nucleic acid binding; embryo development; germ cell development; cytoplasm; mRNA splice site selection; nucleus;
RBFOX1	7	regulation of RNA splicing; RNA binding; nucleotide binding; mRNA processing; cytoplasm; protein binding; nucleus;
HNRNPA2B1	7	ribonucleoprotein complex; RNA binding; nucleotide binding; mRNA processing; cytoplasm; protein binding; nucleus;
RBM4	7	RNA binding; mRNA binding; nucleotide binding; mRNA processing; cytoplasm; protein binding; nucleus;
HNRNPH1	6	regulation of RNA splicing; RNA binding; nucleotide binding; cytoplasm; protein binding; nucleus;
HNRNPA1	6	ribonucleoprotein complex; RNA binding; nucleotide binding; mRNA processing; cytoplasm; nucleus;
TRIM32	5	translation initiation factor binding; RNA binding; cytoplasm; protein binding; nucleus;
ATXN2	5	ribonucleoprotein complex; RNA binding; cytoplasm; protein binding; nucleus;
IGHMBP2	5	ribonucleoprotein complex; RNA binding; cytoplasm; protein binding; nucleus;
LARP7	5	ribonucleoprotein complex; RNA binding; nucleotide binding; cytoplasm; nucleus;
NCBP1	5	ribonucleoprotein complex; RNA binding; mRNA processing; protein binding; nucleus;
NSRP1	5	ribonucleoprotein complex; mRNA binding; mRNA processing; protein binding; nucleus;
RBM14	5	ribonucleoprotein complex; RNA binding; nucleotide binding; protein binding; nucleus;
RPS3	5	ribonucleoprotein complex; mRNA binding; cytoplasm; protein binding; nucleus;
CPSF7	5	RNA binding; nucleotide binding; mRNA processing; protein binding; nucleus;
FUS	5	RNA binding; nucleotide binding; cytoplasm; protein binding; nucleus;
IGF2BP3	5	RNA binding; nucleotide binding; cytoplasm; protein binding; nucleus;
NOL8	5	RNA binding; nucleotide binding; cytoplasm; protein binding; nucleus;
PSPC1	5	RNA binding; nucleotide binding; cytoplasm; protein binding; nucleus;
SMNDC1	5	RNA binding; mRNA processing; cytoplasm; protein binding; nucleus;
TARDBP	5	RNA binding; nucleotide binding; mRNA processing; protein binding; nucleus;
U2AF1	5	RNA binding; nucleotide binding; mRNA processing; protein binding; nucleus;

Genes shared at least 2 KEGG pathways with CELF1 (count: 0)

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Region: chr11:47487489..47587121 View in gBrowse