ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MED23
Previous Symbol	CRSP3
Symbol Alias	CRSP130, DRIP130, Sur2
Approved Name	mediator complex subunit 23
Previous Name	cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa
Location	6q22.33-q24.1
Position	chr6:131895106-131949369, -
External Links	HGNC: 2372 Entrez Gene: 9439 Ensembl: ENSG00000112282 UCSC: uc003qcs.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 9)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0016592	mediator complex	Cellular Component		17
GO:0003713	transcription coactivator activity	Molecular Function	TAS[9989412]	52
GO:0005515	protein binding	Molecular Function	IPI[17438371]	910
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005667	transcription factor complex	Cellular Component	IDA[9989412]	51
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA[9989412]	158
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	TAS[9989412]	42
GO:0006367	transcription initiation from RNA polymerase II promoter	Biological Process		42
GO:0010467	gene expression	Biological Process		140

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MED23 (count: 19)

Gene Symbol	Pathway Count	Pathway List
MED7	8	mediator complex; transcription coactivator activity; protein binding; nucleoplasm; transcription factor complex; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; gene expression;
MED17	7	mediator complex; transcription coactivator activity; nucleoplasm; transcription factor complex; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; gene expression;
MED1	6	mediator complex; transcription coactivator activity; protein binding; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
MED14	6	mediator complex; transcription coactivator activity; nucleoplasm; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; gene expression;
MED16	6	mediator complex; transcription coactivator activity; nucleoplasm; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; gene expression;
SNW1	6	transcription coactivator activity; protein binding; nucleoplasm; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; gene expression;
YAP1	6	transcription coactivator activity; protein binding; nucleoplasm; transcription factor complex; transcription initiation from RNA polymerase II promoter; gene expression;
MED12	5	mediator complex; transcription coactivator activity; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
MED13	5	mediator complex; transcription coactivator activity; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
MED15	5	mediator complex; protein binding; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
MED24	5	mediator complex; nucleoplasm; regulation of transcription, DNA-dependent; transcription initiation from RNA polymerase II promoter; gene expression;
MED30	5	mediator complex; protein binding; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
MED4	5	mediator complex; protein binding; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
MAML1	5	transcription coactivator activity; protein binding; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
NCOA6	5	transcription coactivator activity; protein binding; nucleoplasm; transcription factor complex; transcription initiation from RNA polymerase II promoter;
NR5A1	5	transcription coactivator activity; protein binding; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
TAF10	5	transcription coactivator activity; protein binding; nucleoplasm; transcription initiation from RNA polymerase II promoter; gene expression;
E2F5	5	protein binding; nucleoplasm; transcription factor complex; transcription initiation from RNA polymerase II promoter; gene expression;
NCOR1	5	protein binding; nucleoplasm; transcription factor complex; transcription initiation from RNA polymerase II promoter; gene expression;

Genes shared at least 2 KEGG pathways with MED23 (count: 0)

View in gBrowse

Region: chr6:131895106..131949369 View in gBrowse