ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006367
Name transcription initiation from RNA polymerase II promoter
Type biological process
No. of Genes in ADHDgene  44
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 44)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MED27 mediator complex subunit 27 9q34.13 1(0/1/0) TAS
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 8q24 1(0/1/0) IDA[9418870]
NR4A2 nuclear receptor subfamily 4, group A, member 2 2q22-q23 2(0/2/0) TAS
NR3C2 nuclear receptor subfamily 3, group C, member 2 4q31 1(0/1/0) TAS

Genes from other sources Help (count: 40)

Approved Symbol Approved Name Source Evidence[PMID]
CREBBP CREB binding protein Mapped by significant region TAS
MED30 mediator complex subunit 30 Mapped by PBA pathway IDA[12218053]; TAS
MED10 mediator complex subunit 10 Mapped by significant region TAS
PGR progesterone receptor Mapped by significant region TAS
MED4 mediator complex subunit 4 Mapped by PBA pathway IDA[12218053]; TAS
MED14 mediator complex subunit 14 Mapped by PBA pathway IDA[12218053]; TAS
MEN1 multiple endocrine neoplasia I Mapped by significant region TAS
MED12 mediator complex subunit 12 Mapped by PBA pathway IDA[12218053]; TAS
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa Mapped by significant region TAS
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) Mapped by CNV IDA[1502157]
NR6A1 nuclear receptor subfamily 6, group A, member 1 Mapped by significant region TAS
MED7 mediator complex subunit 7 Mapped by significant region TAS
UBC ubiquitin C Mapped by CNV TAS
YAP1 Yes-associated protein 1 Mapped by significant region TAS
MED16 mediator complex subunit 16 Mapped by PBA pathway IDA[12218053]; TAS
SNW1 SNW domain containing 1 Mapped by PBA pathway TAS
MED24 mediator complex subunit 24 Mapped by PBA pathway IDA[12218053]; TAS
MED13 mediator complex subunit 13 Mapped by PBA pathway IDA[12218053]; TAS
ESRRA estrogen-related receptor alpha Mapped by significant region TAS
MED23 mediator complex subunit 23 Mapped by significant region TAS
MAML1 mastermind-like 1 (Drosophila) Mapped by CNV TAS
RORA RAR-related orphan receptor A Mapped by Literature SNP TAS
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway ISS
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IDA[12218053]; TAS
RBPJ recombination signal binding protein for immunoglobulin kappa J region Mapped by CNV TAS
NR5A1 nuclear receptor subfamily 5, group A, member 1 Mapped by significant region TAS
THRAP3 thyroid hormone receptor associated protein 3 Mapped by PBA pathway IDA[12218053]
NRBP1 nuclear receptor binding protein 1 Mapped by PBA pathway TAS
NCOR2 nuclear receptor corepressor 2 Mapped by CNV TAS
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa Mapped by CNV IC[7729427]; IDA[9603525]; TAS
MED17 mediator complex subunit 17 Mapped by significant region; Mapped by PBA pathway IDA[12218053]; TAS
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa Mapped by CNV TAS
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa Mapped by CNV IC[7729427]; TAS
MED15 mediator complex subunit 15 Mapped by CNV TAS
CTGF connective tissue growth factor Mapped by significant region TAS
UBB ubiquitin B Mapped by significant region TAS
POLR2G polymerase (RNA) II (DNA directed) polypeptide G Mapped by significant region TAS
MAML2 mastermind-like 2 (Drosophila) Mapped by significant region TAS
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase Mapped by significant region TAS
MED20 mediator complex subunit 20 Mapped by CNV TAS