ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TAF1B
Symbol Alias	TAFI63, SL1, RAF1B, RAFI63
Approved Name	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
Previous Name	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD
Location	2p25
Position	chr2:9973981-10074545, +
External Links	HGNC: 11533 Entrez Gene: 9014 Ensembl: ENSG00000115750 UCSC: uc002qzz.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2p25.1	chr2:7100000-12200000	2 (1/0/1)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006363	termination of RNA polymerase I transcription	Biological Process		4
GO:0010467	gene expression	Biological Process		140
GO:0006361	transcription initiation from RNA polymerase I promoter	Biological Process		6
GO:0006362	transcription elongation from RNA polymerase I promoter	Biological Process		4
GO:0070860	RNA polymerase I core factor complex	Cellular Component		1
GO:0017025	TBP-class protein binding	Molecular Function		1
GO:0046872	metal ion binding	Molecular Function		170
GO:0001187	RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity	Molecular Function		1
GO:0001164	RNA polymerase I CORE element sequence-specific DNA binding	Molecular Function		1
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	NAS[7801123]	132
GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript	Biological Process		1
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005634	nucleus	Cellular Component	NAS[7801123]	770
GO:0006360	transcription from RNA polymerase I promoter	Biological Process		6
GO:0006351	transcription, DNA-dependent	Biological Process	NAS[7801123]	247

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TAF1B (count: 5)

Gene Symbol	Pathway Count	Pathway List
GTF2H3	8	termination of RNA polymerase I transcription; gene expression; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase I promoter; metal ion binding; sequence-specific DNA binding transcription factor activity; nucleoplasm; transcription from RNA polymerase I promoter;
POLR1A	6	termination of RNA polymerase I transcription; gene expression; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase I promoter; nucleoplasm; transcription from RNA polymerase I promoter;
TAF1C	6	termination of RNA polymerase I transcription; gene expression; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase I promoter; nucleoplasm; transcription from RNA polymerase I promoter;
MAPK3	5	gene expression; transcription initiation from RNA polymerase I promoter; nucleoplasm; nucleus; transcription from RNA polymerase I promoter;
NCOR1	5	gene expression; sequence-specific DNA binding transcription factor activity; nucleoplasm; nucleus; transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with TAF1B (count: 0)

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Region: chr2:9973981..10074545 View in gBrowse