ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	NR4A3
Symbol Alias	CSMF, CHN, NOR1, MINOR
Approved Name	nuclear receptor subfamily 4, group A, member 3
Location	9q22
Position	chr9:102584137-102629173, +
External Links	HGNC: 7982 Entrez Gene: 8013 Ensembl: ENSG00000119508 UCSC: uc004bai.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)
9q22	chr9:90400000-102600000	3 (1/1/1)

Gene related GO terms (count: 25)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 25)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:2000108	positive regulation of leukocyte apoptotic process	Biological Process		1
GO:0045787	positive regulation of cell cycle	Biological Process		7
GO:0048752	semicircular canal morphogenesis	Biological Process		3
GO:0050885	neuromuscular process controlling balance	Biological Process		8
GO:0060005	vestibular reflex	Biological Process		1
GO:0033554	cellular response to stress	Biological Process		12
GO:0043434	response to peptide hormone stimulus	Biological Process		9
GO:0043524	negative regulation of neuron apoptotic process	Biological Process		19
GO:0043565	sequence-specific DNA binding	Molecular Function		72
GO:0010467	gene expression	Biological Process		140
GO:0021766	hippocampus development	Biological Process		7
GO:0030534	adult behavior	Biological Process		5
GO:0031100	organ regeneration	Biological Process		11
GO:0008270	zinc ion binding	Molecular Function		323
GO:0008150	biological_process	Biological Process		106
GO:0007411	axon guidance	Biological Process		65
GO:0006367	transcription initiation from RNA polymerase II promoter	Biological Process		42
GO:0005667	transcription factor complex	Cellular Component		51
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005634	nucleus	Cellular Component	NAS[8634690]	770
GO:0004887	thyroid hormone receptor activity	Molecular Function	TAS[8570200]	1
GO:0003707	steroid hormone receptor activity	Molecular Function		9
GO:0003677	DNA binding	Molecular Function	NAS[8634690]	220
GO:0001707	mesoderm formation	Biological Process		3
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular Function		8

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NR4A3 (count: 20)

Gene Symbol	Pathway Count	Pathway List
NR4A2	9	cellular response to stress; negative regulation of neuron apoptotic process; sequence-specific DNA binding; gene expression; zinc ion binding; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus; steroid hormone receptor activity;
ESRRA	8	sequence-specific DNA binding; gene expression; zinc ion binding; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus; steroid hormone receptor activity; DNA binding;
NR5A1	8	sequence-specific DNA binding; gene expression; zinc ion binding; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus; steroid hormone receptor activity; DNA binding;
NR6A1	8	sequence-specific DNA binding; gene expression; zinc ion binding; transcription initiation from RNA polymerase II promoter; transcription factor complex; nucleoplasm; steroid hormone receptor activity; DNA binding;
PGR	8	sequence-specific DNA binding; gene expression; zinc ion binding; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus; steroid hormone receptor activity; DNA binding;
NCOR1	6	sequence-specific DNA binding; gene expression; transcription initiation from RNA polymerase II promoter; transcription factor complex; nucleoplasm; nucleus;
NR3C2	6	sequence-specific DNA binding; gene expression; zinc ion binding; transcription initiation from RNA polymerase II promoter; nucleoplasm; steroid hormone receptor activity;
RORA	6	sequence-specific DNA binding; gene expression; zinc ion binding; transcription initiation from RNA polymerase II promoter; nucleoplasm; steroid hormone receptor activity;
RBPJ	6	gene expression; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus; DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;
FOXG1	5	positive regulation of cell cycle; sequence-specific DNA binding; transcription factor complex; nucleus; DNA binding;
MEN1	5	sequence-specific DNA binding; gene expression; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus;
RELA	5	sequence-specific DNA binding; transcription factor complex; nucleoplasm; nucleus; DNA binding;
E2F5	5	gene expression; transcription initiation from RNA polymerase II promoter; transcription factor complex; nucleoplasm; DNA binding;
FUS	5	gene expression; zinc ion binding; nucleoplasm; nucleus; DNA binding;
MED1	5	gene expression; organ regeneration; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus;
MED17	5	gene expression; transcription initiation from RNA polymerase II promoter; transcription factor complex; nucleoplasm; nucleus;
NCOR2	5	gene expression; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus; DNA binding;
TAF13	5	gene expression; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus; DNA binding;
TAF4B	5	gene expression; transcription initiation from RNA polymerase II promoter; nucleoplasm; nucleus; DNA binding;
YAP1	5	gene expression; transcription initiation from RNA polymerase II promoter; transcription factor complex; nucleoplasm; nucleus;

Genes shared at least 2 KEGG pathways with NR4A3 (count: 0)

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Region: chr9:102584137..102629173 View in gBrowse