ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TINF2
Symbol Alias	TIN2
Approved Name	TERF1 (TRF1)-interacting nuclear factor 2
Location	14q12
Position	chr14:24708849-24711880, -
External Links	HGNC: 11824 Entrez Gene: 26277 Ensembl: ENSG00000092330 UCSC: uc001woa.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
14q12	chr14:24600000-33300000	1 (1/0/0)

Gene related GO terms (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0042162	telomeric DNA binding	Molecular Function	IDA[12768206]	4
GO:0034502	protein localization to chromosome	Biological Process	IC[15380063]; IMP[15133513]	1
GO:0070198	protein localization to chromosome, telomeric region	Biological Process	IMP[18443218]	2
GO:0050680	negative regulation of epithelial cell proliferation	Biological Process	IMP[15741234]	5
GO:0032202	telomere assembly	Biological Process	IMP[16880378]	1
GO:0016363	nuclear matrix	Cellular Component		16
GO:0032211	negative regulation of telomere maintenance via telomerase	Biological Process	IC[15133513]; IGI[10581025]	1
GO:0032206	positive regulation of telomere maintenance	Biological Process	IMP[18443218]	1
GO:0010370	perinucleolar chromocenter	Cellular Component	IDA[15741234]	1
GO:0005654	nucleoplasm	Cellular Component		183
GO:0010836	negative regulation of protein ADP-ribosylation	Biological Process	IGI[15133513]	1
GO:0010833	telomere maintenance via telomere lengthening	Biological Process	IMP[18669893]	2
GO:0000723	telomere maintenance	Biological Process		10
GO:0003677	DNA binding	Molecular Function	IDA[10581025]	220
GO:0005515	protein binding	Molecular Function	IPI[15380063]	910
GO:0000781	chromosome, telomeric region	Cellular Component	IDA[15380063]	9
GO:0000783	nuclear telomere cap complex	Cellular Component	IDA[16880378]	3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TINF2 (count: 3)

Gene Symbol	Pathway Count	Pathway List
TERF2IP	8	telomeric DNA binding; protein localization to chromosome, telomeric region; nucleoplasm; telomere maintenance via telomere lengthening; telomere maintenance; protein binding; chromosome, telomeric region; nuclear telomere cap complex;
XRCC5	6	telomeric DNA binding; nucleoplasm; telomere maintenance; DNA binding; protein binding; nuclear telomere cap complex;
ATM	5	nucleoplasm; telomere maintenance; DNA binding; protein binding; chromosome, telomeric region;

Genes shared at least 2 KEGG pathways with TINF2 (count: 0)

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Region: chr14:24708849..24711880 View in gBrowse