ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CBFA2T3
Symbol Alias	MTGR2, ZMYND4, MTG16
Approved Name	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Name Alias	myeloid translocation gene 8 and 16b
Location	16q24
Position	chr16:88941266-89043401, -
External Links	HGNC: 1537 Entrez Gene: 863 Ensembl: ENSG00000129993 UCSC: uc002fmm.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 11)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000139	Golgi membrane	Cellular Component		95
GO:0003682	chromatin binding	Molecular Function		48
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process		131
GO:0008270	zinc ion binding	Molecular Function		323
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0030851	granulocyte differentiation	Biological Process	IDA[15231665]	4
GO:0008283	cell proliferation	Biological Process	TAS[9447981]	60
GO:0005515	protein binding	Molecular Function	IPI[16966434]	910
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0005730	nucleolus	Cellular Component		243
GO:0005654	nucleoplasm	Cellular Component		183

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CBFA2T3 (count: 24)

Gene Symbol	Pathway Count	Pathway List
KDM1A	8	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; granulocyte differentiation; cell proliferation; protein binding; sequence-specific DNA binding transcription factor activity; nucleoplasm;
HINFP	7	chromatin binding; zinc ion binding; transcription, DNA-dependent; protein binding; sequence-specific DNA binding transcription factor activity; nucleolus; nucleoplasm;
SREBF1	6	Golgi membrane; chromatin binding; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; protein binding; sequence-specific DNA binding transcription factor activity;
GATA6	6	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; zinc ion binding; protein binding; sequence-specific DNA binding transcription factor activity; nucleoplasm;
MEN1	6	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; protein binding; nucleolus; nucleoplasm;
MTA2	6	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; zinc ion binding; protein binding; sequence-specific DNA binding transcription factor activity; nucleolus;
ATF6	5	Golgi membrane; transcription, DNA-dependent; protein binding; sequence-specific DNA binding transcription factor activity; nucleoplasm;
MED1	5	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleolus; nucleoplasm;
MYB	5	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; protein binding; sequence-specific DNA binding transcription factor activity;
NCOA6	5	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; protein binding; nucleolus; nucleoplasm;
NCOR1	5	chromatin binding; transcription, DNA-dependent; protein binding; sequence-specific DNA binding transcription factor activity; nucleoplasm;
NCOR2	5	chromatin binding; transcription, DNA-dependent; protein binding; nucleolus; nucleoplasm;
NR5A1	5	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; zinc ion binding; protein binding; nucleoplasm;
RELA	5	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; protein binding; sequence-specific DNA binding transcription factor activity; nucleoplasm;
RNF2	5	chromatin binding; zinc ion binding; transcription, DNA-dependent; protein binding; nucleolus;
YAP1	5	chromatin binding; positive regulation of transcription from RNA polymerase II promoter; cell proliferation; protein binding; nucleoplasm;
ATXN1	5	positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; protein binding; nucleolus; nucleoplasm;
E2F5	5	positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; protein binding; sequence-specific DNA binding transcription factor activity; nucleoplasm;
NR4A2	5	positive regulation of transcription from RNA polymerase II promoter; zinc ion binding; transcription, DNA-dependent; protein binding; nucleoplasm;
POU2F3	5	positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; protein binding; sequence-specific DNA binding transcription factor activity; nucleolus;
RBPJ	5	positive regulation of transcription from RNA polymerase II promoter; protein binding; sequence-specific DNA binding transcription factor activity; nucleolus; nucleoplasm;
RORA	5	positive regulation of transcription from RNA polymerase II promoter; zinc ion binding; protein binding; sequence-specific DNA binding transcription factor activity; nucleoplasm;
SMARCB1	5	positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; protein binding; nucleolus; nucleoplasm;
XRCC5	5	transcription, DNA-dependent; cell proliferation; protein binding; nucleolus; nucleoplasm;

Genes shared at least 2 KEGG pathways with CBFA2T3 (count: 0)

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Region: chr16:88941266..89043401 View in gBrowse