ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0008283
Name	cell proliferation
Type	Biological Process
No. of Genes in ADHDgene	60
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 60)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
ADRA1D	adrenergic, alpha-1D-, receptor	20p13	1(0/1/0)	TAS[10820200]
GFI1B	growth factor independent 1B transcription repressor	9q34.13	1(0/1/0)	TAS[9566867]
ADRA1B	adrenergic, alpha-1B-, receptor	5q33.3	2(1/1/0)	TAS[10820200]
EMP2	epithelial membrane protein 2	16p13.2	2(0/0/2)	TAS[8996089]
FURIN	furin (paired basic amino acid cleaving enzyme)	15q26.1	1(0/0/1)	IMP[15899807]

Genes from other sources (count: 55)

Approved Symbol	Approved Name	Source	Evidence[PMID]
CTF1	cardiotrophin 1	Mapped by CNV	TAS[7738033]
PELO	pelota homolog (Drosophila)	Mapped by LD-proxy; Mapped by literature SNP
PLK1	polo-like kinase 1	Mapped by significant region	TAS[8127874]
CCKBR	cholecystokinin B receptor	Mapped by CNV; Mapped by PBA pathway	TAS[10400698]
ZNF259	zinc finger protein 259	Mapped by significant region	TAS[9763455]
FES	feline sarcoma oncogene	Mapped by LD-proxy	TAS[6264598]
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	Mapped by significant region	TAS[9447981]
MAPRE1	microtubule-associated protein, RP/EB family, member 1	Mapped by PBA pathway	TAS[7606712]
YAP1	Yes-associated protein 1	Mapped by significant region	IDA[17974916]
SYK	spleen tyrosine kinase	Mapped by significant region	TAS[10963601]
OCA2	oculocutaneous albinism II	Mapped by CNV; Mapped by significant region
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	Mapped by significant region
IFLTD1	intermediate filament tail domain containing 1	Mapped by CNV
KIF2C	kinesin family member 2C	Mapped by PBA pathway	TAS[9434124]
SKP2	S-phase kinase-associated protein 2 (p45)	Mapped by significant region	TAS[7553852]
CKS2	CDC28 protein kinase regulatory subunit 2	Mapped by significant region	TAS[8211159]
TXN	thioredoxin	Mapped by significant region	TAS[3170595]
PEMT	phosphatidylethanolamine N-methyltransferase	Mapped by significant region	TAS[9989271]
PRKD1	protein kinase D1	Mapped by significant region	TAS[8119958]
EDNRA	endothelin receptor type A	Mapped by PBA pathway	NAS[9284755]
MS4A2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	Mapped by PBA pathway; Mapped by significant region	TAS[2448768]
SIPA1	signal-induced proliferation-associated 1	Mapped by significant region	TAS[9346962]
SLC29A2	solute carrier family 29 (nucleoside transporters), member 2	Mapped by significant region	TAS[7639753]
TBX1	T-box 1	Mapped by CNV
RRN3	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)	Mapped by CNV; Mapped by significant region
CD5	CD5 molecule	Mapped by significant region	NAS[3093892]
MAP3K11	mitogen-activated protein kinase kinase kinase 11	Mapped by significant region	IMP[15258589]
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region	TAS[10639512]
PLCE1	phospholipase C, epsilon 1	Mapped by PBA pathway	NAS[11022048]
REG1B	regenerating islet-derived 1 beta	Mapped by CNV	TAS[2963000]
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	Mapped by LD-proxy	TAS[10851066]
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	Mapped by significant region
REG3A	regenerating islet-derived 3 alpha	Mapped by CNV	TAS[8997243]
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	Mapped by significant region	TAS[9620555]
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	Mapped by significant region	TAS[8391931]
GLUL	glutamate-ammonia ligase	Mapped by significant region	IDA[18662667]
PAK7	p21 protein (Cdc42/Rac)-activated kinase 7	Mapped by CNV
KDM1A	lysine (K)-specific demethylase 1A	Mapped by LD-proxy
ACHE	acetylcholinesterase	Mapped by PBA pathway	TAS[11283752]
CHRM1	cholinergic receptor, muscarinic 1	Mapped by PBA pathway; Mapped by significant region	TAS[1905013]
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mapped by CNV	IDA[12782713]
MAPRE2	microtubule-associated protein, RP/EB family, member 2	Mapped by significant region	TAS[9233623]
CUL5	cullin 5	Mapped by PBA pathway; Mapped by significant region	TAS[9037604]
IL5RA	interleukin 5 receptor, alpha	Mapped by CNV	TAS[1732409]
CHRM5	cholinergic receptor, muscarinic 5	Mapped by CNV; Mapped by PBA pathway	TAS[8063729]
NPY	neuropeptide Y	Mapped by CNV; Mapped by significant region	TAS[10488139]
NR6A1	nuclear receptor subfamily 6, group A, member 1	Mapped by significant region	TAS[9134503]
GOLPH3	golgi phosphoprotein 3 (coat-protein)	Mapped by significant region	IMP[19553991]
CHRM3	cholinergic receptor, muscarinic 3	Mapped by CNV; Mapped by PBA pathway	TAS[8063729]
USP28	ubiquitin specific peptidase 28	Mapped by significant region	IMP[17558397]
TYR	tyrosinase (oculocutaneous albinism IA)	Mapped by significant region
ILK	integrin-linked kinase	Mapped by CNV	NAS[10871859]
OSMR	oncostatin M receptor	Mapped by significant region	TAS[8999038]
LIPG	lipase, endothelial	Mapped by PBA pathway
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	Mapped by significant region